Anti-NUDCD1 antibody produced in rabbit

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

Anti-NudC domain-containing protein 1, Anti-Chronic myelogenous leukemia tumor antigen 66, Anti-Tumor antigen CML66
Human Protein Atlas Number:

biological source


Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies



product line

Prestige Antibodies® Powered by Atlas Antibodies


buffered aqueous glycerol solution

species reactivity

rat, human


antibody small pack of 25 μL


immunoblotting: 0.04-0.4 μg/mL
immunofluorescence: 0.25-2 μg/mL
immunohistochemistry: 1:20-1:50

immunogen sequence




UniProt accession no.

shipped in

wet ice

storage temp.


Gene Information

human ... NUDCD1(84955)

General description

The gene NUDCD1 (NudC domain containing 1) is mapped to human chromosome 8q23.


NudC domain-containing protein 1 recombinant protein epitope signature tag (PrEST)

Biochem/physiol Actions

NUDCD1 (NudC domain containing 1) is strongly expressed in leukemia cells, mainly in CD34+ myeloid progenitor cells. It is a tumor-associated antigen. NUDCD1 is also upregulated in lung cancer and prostate cancer. In tumor cells, decrease in expression of NUDCD1 suppresses proliferation, invasion and metastasis.

Features and Benefits

Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:
  • IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
  • Protein array of 364 human recombinant protein fragments.


Corresponding Antigen APREST76220.

Physical form

Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide

Legal Information

Prestige Antibodies is a registered trademark of Sigma-Aldrich Co. LLC


NONH for all modes of transport

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Identification of a novel epitope derived from CML66 that is recognized by anti-leukaemia cytotoxic T lymphocytes.
Koichiro Suemori et al.
British journal of haematology, 146(1), 115-118 (2009-04-25)
Wandi Zhang et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 16(10), 2729-2739 (2010-05-13)
The target antigens of graft-versus-leukemia that are tumor associated are incompletely characterized. We examined responses developing against CML66, an immunogenic antigen preferentially expressed in myeloid progenitor cells identified from a patient with chronic myelogenous leukemia who attained long-lived remission following...
Miriam Ragle Aure et al.
PloS one, 8(1), e53014-e53014 (2013-02-06)
Genomic copy number alterations are common in cancer. Finding the genes causally implicated in oncogenesis is challenging because the gain or loss of a chromosomal region may affect a few key driver genes and many passengers. Integrative analyses have opened...

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