M Makishima et al.
FEBS letters, 287(1-2), 175-177 (1991-08-05)
Inhibitors of myosin light chain kinase, 1-(5-chloronaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride (ML-9) and 1-(5-iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride (ML-7), induced Nitroblue tetrazolium reducing activity, lysozyme activity and morphological maturation of human monoblastic U937, THP-1 and promyelocytic HL-60 cells, but not of erythroblastic K562 cells. However, three...
Kristopher E Kubow et al.
Scientific reports, 7(1), 14380-14380 (2017-11-01)
Contact guidance-cell polarization by anisotropic substrate features-is integral to numerous physiological processes; however the complexities of its regulation are only beginning to be discovered. In particular, cells polarize to anisotropic features under non-muscle myosin II (MII) inhibition, despite MII ordinarily...
Inhibition of myosin light chain kinase can be targeted for the development of new therapies against herpes simplex virus type-1 infection
Antoine TE and Shukla D
Antiviral Therapy, 19, 15-29 (2014)
Zasp/Cypher internal ZM-motif containing fragments are sufficient to co-localize with alpha-actinin?Analysis of patient mutations
Klaavuniemi T and Ylanne J
Experimental Cell Research, 312(8), 1299-1311 (2006)
Sylvain Recoquillon et al.
Scientific reports, 7(1), 13664-13664 (2017-10-24)
Obstructive sleep apnea is characterized by intermittent hypoxia (IH) which alters endothelial function, induces inflammation and accelerates atherosclerosis-induced cardiovascular diseases. The non-muscular myosin light chain kinase (nmMLCK) isoform contributes to endothelial cell-cell junction opening. Deletion of nmMLCK protects mice from...