I4036

Sigma-Aldrich

IgA from human serum

reagent grade, ≥95% (HPLC), buffered aqueous solution

NACRES:
NA.41

Quality Level

grade

reagent grade

assay

≥95% (HPLC)

form

buffered aqueous solution

conjugate

unconjugated

storage temp.

−20°C

Application

Purified human IgA may be used to study its physiological and biological effects on processes such as inflammation, pathogen elimination, regulation of antibody-dependent-cell-mediated cytotoxicity (ADCC), modulation of phagocytosis, degranulation of eosinophils and basophils and modulation of respiratory burst activity.

Physical form

Solution in 0.01 M Phosphate Buffer saline, pH 7.4, containing 15 mM sodium azide as a preservative.

RIDADR

NONH for all modes of transport

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Qiao Zhong et al.
Journal of immunology (Baltimore, Md. : 1950), 200(12), 3913-3925 (2018-05-02)
Prevalence of circulating immunocomplexes (ICs) strongly correlates with rheumatoid arthritis (RA) in humans. Deposits of IgG-ICs are abundant in affected joints of patients, yet molecular mechanisms for the pathogenic roles of such ICs are not fully understood. In this study...
Baweleta Isho et al.
Science immunology, 5(52) (2020-10-10)
While the antibody response to SARS-CoV-2 has been extensively studied in blood, relatively little is known about the antibody response in saliva and its relationship to systemic antibody levels. Here, we profiled by enzyme-linked immunosorbent assays (ELISAs) IgG, IgA and...
Biodistribution and serologic response in SARS-CoV-2 induced ARDS: A cohort study.
Schlesinger, et al.
PLoS ONE, 15, e0242917-e0242917 (2020)

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