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I4161

Sigma-Aldrich

Interleukin-2 from mouse

IL-2, recombinant, expressed in E. coli, carrier free

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Synonym(s):
mIL-2, IL-2, T-cell growth factor
MDL number:
NACRES:
NA.77

biological source

mouse

Quality Level

recombinant

expressed in E. coli

Assay

≥97% (SDS-PAGE)

form

lyophilized powder

potency

≤0.2 ng/mL ED50

quality

endotoxin tested

mol wt

17.2 kDa

packaging

pkg of 5X20 μg
pkg of 20 μg

technique(s)

cell culture | mammalian: suitable

impurities

≤0.200ng/ml

color

white

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

mouse ... Il2(16183)

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This Item
I0523I3019I7908
Sigma-Aldrich

Sigma-Aldrich

I7908

Interleukin-2 human

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in Pichia pastoris

assay

≥97% (SDS-PAGE)

assay

≥97% (SDS-PAGE)

assay

>97% (SDS-PAGE)

assay

≥98% (SDS-PAGE and HPLC)

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

potency

≤0.2 ng/mL ED50

potency

≤0.2 ng/mL ED50

potency

0.01-1.50 ng/mL EC50

potency

-

mol wt

17.2 kDa

mol wt

17.2 kDa

mol wt

~18 kDa

mol wt

predicted mol wt ~15 kDa

Biochem/physiol Actions

Interleukin-2 (IL-2) is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. Recombinant human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfide bond.

Physical form

Lyophilized with no additives.

Reconstitution

Centrifuge vial prior to opening. Reconstitute the contents of the vial in water to a concentration range of 0.1-1.0 mg/mL.
IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfide bond.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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