I5152

Anti-Interferon-γ Receptor 1 (IFN-γ R1) antibody produced in goat

affinity isolated antibody, lyophilized powder

• Synonym(s): Anti-CD119, Anti-IFNGR, Anti-IMD27A, Anti-IMD27B
• MDL number: MFCD03455331
• UNSPSC Code: 51111800
• NACRES: NA.41

Properties

• biological source: goat
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• species reactivity: human
• technique(s): immunocytochemistry: 5-15 μg/mL using immersion fixed human peripheral blood mononuclear cells; neutralization: suitable; western blot: 0.1 μg/mL
• isotype: IgG
• UniProt accession no.: P15260
• Storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... IFNGR1(3459)

Description

General description

Human Interferon-γ- Receptor I (IFN-γ RI) is a 25kD, 227 amino acid residue containing protein that belongs to type II cytokine receptor family. IFN-γ RI has a crucial role in ligand-binding and signaling. Ligand IFN-γ induces tyrosine phosphorylation in IFN-γ RI which in turn leads to the formation of a docking site on the activated receptor for Stat1 that specifically activates IFN-γ induced gene transcription. Anti-Interferon γ Receptor I (IFN-γ RI) antibody can be used in neutralization assay using a confluent culture of HeLa cells. Goat anti-Interferon γ Receptor I (IFN-γ RI) antibody reacts specifically with recombinant human IFN-γ RI. The product has shown no cross-reactivity for recombinant human IFN-γ RII.

Immunogen

recombinant human IFN-γ Receptor I extracellular domain expressed in NSO cells.

Application

Anti-Interferon γ Receptor I (IFN-γ RI) antibody can be used in indirect ELISA and western blot.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable