MilliporeSigma
All Photos(1)

Documents

I5385

Sigma-Aldrich

Monoclonal Anti-Human IgG1 (Fab specific) [G1m(f)] antibody produced in mouse

clone SG-16, ascites fluid

All Photos(1)
MDL number:
MFCD00164656
NACRES:
NA.46

biological source

mouse

Quality Level

200

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

secondary antibodies

clone

SG-16, monoclonal

contains

15 mM sodium azide

technique(s)

indirect ELISA: 1:5,000

isotype

IgG1

shipped in

dry ice

storage temp.

−20°C

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
I6260I5885I6760
Monoclonal Anti-Human IgG1 (Fab specific) [G1m(f)] antibody produced in mouse clone SG-16, ascites fluid

Sigma-Aldrich

I5385

Monoclonal Anti-Human IgG1 (Fab specific) [G1m(f)] antibody produced in mouse

Monoclonal Anti-Human IgG (Fc specific) antibody produced in mouse clone GG-7, ascites fluid

Sigma-Aldrich

I6260

Monoclonal Anti-Human IgG (Fc specific) antibody produced in mouse

Monoclonal Anti-Human IgG (γ-chain specific) antibody produced in mouse clone GG-5, ascites fluid

Sigma-Aldrich

I5885

Monoclonal Anti-Human IgG (γ-chain specific) antibody produced in mouse

Monoclonal Anti-Human IgG (Fc specific) antibody produced in mouse clone HP-6017, ascites fluid

Sigma-Aldrich

I6760

Monoclonal Anti-Human IgG (Fc specific) antibody produced in mouse

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

antibody form

ascites fluid

antibody form

ascites fluid

antibody form

ascites fluid

antibody form

ascites fluid

clone

SG-16, monoclonal

clone

GG-7, monoclonal

clone

GG-5, monoclonal

clone

HP-6017, monoclonal

technique(s)

indirect ELISA: 1:5,000

technique(s)

indirect ELISA: 1:40,000

technique(s)

indirect ELISA: 1:20,000

technique(s)

indirect ELISA: 1:3,000

isotype

IgG1

isotype

IgG1

isotype

IgG1

isotype

IgG2a

General description

Monoclonal Anti-Human IgG1 (mouse IgG1isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. Human IgGs are glycoprotein antibodies that contain two equivalent light chains and a pair of identical heavy chains. IgGs have four distinct isoforms, ranging from IgG1 to IgG4.

Immunogen

Purified human IgG

Application

Monoclonal anti-Human IgG1 may be used for the identification of human IgG1 subclass by means of various immunoassays. It can be used in direct hemagglutination (HA) and hemagglutination inhibition (HAI) assays, immunofluorometric assay (IFMA) and detection of cytoplasmic IgG. Monoclonal anti-human IgG1 has been used in enzyme linked immunosorbent assay (ELISA).

Biochem/physiol Actions

Human IgGs regulate immunological responses to allergy and pathogenic infections. IgGs have also been implicated in complement fixation and autoimmune disorders This product clone recognizes the G1m(f) allotype and has been established as a useful human IgG1 specificity standard by the WHO/IUIS study.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (Example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Andreas Lossius et al.
Annals of clinical and translational neurology, 4(10), 756-761 (2017-10-20)
Immunoglobulin gamma (IgG) heavy chain genes are associated with susceptibility to multiple sclerosis (MS) and IgG levels in the cerebrospinal fluid (CSF). However, how these variants are implicated in disease mechanisms remains unknown. Here, we show that proliferating plasmablasts expressing
Recurrence of monoclonal gammopathy associated with donor-derived myelodysplastic syndrome after cord blood stem cell transplantation
Yamazaki R, et al.
Experimental Hematology, 39(12), 1119-1123 (2011)
Kenneth A Rogers et al.
Journal of immunology (Baltimore, Md. : 1950), 177(6), 3848-3856 (2006-09-05)
Ig Fc receptors bind to immune complexes through interactions with the Fc regions of specific Ab subclasses to initiate or inhibit the defense mechanisms of the leukocytes on which they are expressed. The mechanism of action of IgG-based therapeutic molecules
Allotype analysis to distinguish the origin of varicella-zoster virus immunoglobulin G after allogeneic stem cell transplantation
Yamazaki R, et al.
Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation, 19(7), 1013-1020 (2013)
R Yamazaki et al.
Transplant infectious disease : an official journal of the Transplantation Society, 16(6), 904-913 (2014-11-05)
Cytomegalovirus (CMV) reactivation still remains a major problem following allogeneic hematopoietic stem cell transplantation (HSCT). In this study, we analyzed an immunoglobulin allotype, IgG1m(f), in CMV-seropositive HSCT recipients and their donors to distinguish donor-derived antibody from recipient-derived antibody. Eight donor-recipient
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service