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MilliporeSigma

I5396

IL-1α mouse

≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Synonym(s):

Interleukin-1α, mIL-1α, IL-1α

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5 μG

$484.00

25 μG

$1,300.00

$484.00


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About This Item

UNSPSC Code:
12352202
NACRES:
NA.77
MDL number:
Biological source:
mouse
Recombinant:
expressed in E. coli
Assay:
≥97% (SDS-PAGE)
Form:
lyophilized powder
Mol wt:
18 kDa
Impurities:
<0.1 EU/μg

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Product Name

Interleukin-1α from mouse, IL-1α, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

biological source

mouse

recombinant

expressed in E. coli

assay

≥97% (SDS-PAGE)

form

lyophilized powder

potency

3-7 pg/mL ED50

quality

endotoxin tested

mol wt

18 kDa

packaging

pkg of 5 and 25 μg

technique(s)

cell culture | mammalian: suitable

impurities

<0.1 EU/μg

UniProt accession no.

storage temp.

−20°C

Quality Level

Gene Information

mouse ... IL1A(3552)

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This Item
I4026I0523I1896
assay

≥97% (SDS-PAGE)

assay

≥97% (SDS-PAGE)

assay

≥97% (SDS-PAGE)

assay

≥97% (SDS-PAGE)

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

Analysis Note

The biological activity is measured in a cel proliferation assay using the murine helper T cell line, D10.G4.1.

Biochem/physiol Actions

Interleukin-1 (IL-1), originally known as Lymphocyte Activating Factor (LA F), activates T cells and lymphocytes, which then proliferate and secrete Interleukin-2 (IL-2). The proliferative activity of human IL-1α is tested in culture using the murine cell line D10S.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.25 mg bovine serum albumin.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Katiria Soto-Díaz et al.
Journal of neurochemistry, 152(6), 697-709 (2019-11-30)
Systemic inflammation can exacerbate symptoms of many neurological diseases. This effect may be facilitated by glial cells of the central nervous system (CNS) that alter their transcriptional responses and up-regulate cytokine and chemokine expression which can, in turn trigger immune
Symons, J.A., et al. et al.
Lymphokines and Interferons, A Practical Approach, 272-272 (1987)

Articles

Interleukins, released from leukocytes, include IL-1β playing crucial roles in inflammation, immune responses, and anti-tumor immunity.

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