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  • I6659
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I6659

Sigma-Aldrich

Imperatorin

≥98% (HPLC), powder

Synonym(s):
8-Isopentenyloxypsoralene, 9-(3-Methylbut-2-enyloxy)-7H-furo[3,2-g]chromen-7-one, 9-[(3-Methyl-2-buten-1-yl)oxy]-7h-furo[3,2-g][1]benzopyran-7-one, Ammidin, Marmelide, Marmelosin, NSC 402949
Empirical Formula (Hill Notation):
C16H14O4
CAS Number:
Molecular Weight:
270.28
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77

Quality Level

Assay

≥98% (HPLC)

form

powder

color

off-white to light brown

solubility

DMSO: ≥5 mg/mL

storage temp.

2-8°C

SMILES string

C\C(C)=C\COc1c2OC(=O)C=Cc2cc3ccoc13

InChI

1S/C16H14O4/c1-10(2)5-7-19-16-14-12(6-8-18-14)9-11-3-4-13(17)20-15(11)16/h3-6,8-9H,7H2,1-2H3

InChI key

OLOOJGVNMBJLLR-UHFFFAOYSA-N

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This Item
PHL89715Y0001205SML2795
Imperatorin ≥98% (HPLC), powder

Sigma-Aldrich

I6659

Imperatorin

Imperatorin phyproof® Reference Substance

PHL89715

Imperatorin

Imperatorin European Pharmacopoeia (EP) Reference Standard

Y0001205

Imperatorin

IMP-1700 ≥98% (HPLC)

Sigma-Aldrich

SML2795

IMP-1700

assay

≥98% (HPLC)

assay

≥95.0% (HPLC)

assay

-

assay

≥98% (HPLC)

form

powder

form

-

form

-

form

powder

color

off-white to light brown

color

-

color

-

color

white to beige

solubility

DMSO: ≥5 mg/mL

solubility

-

solubility

-

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Quality Level

100

Quality Level

-

Quality Level

-

Quality Level

100

Biochem/physiol Actions

Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
Imperatorin is an important bioactive furanocoumarin. It is used to treat neurodegenerative diseases. It possesses anticancer, antibacterial, anti-inflammatory and HIV replication-inhibiting activities. Imperatorin serves as an inhibitor of acetylcholinesterase (AChE) and may help in treating Alzheimer′s disease (AD) and Parkinson′s disease (PD).

Features and Benefits

This compound is featured on the MAPKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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