Skip to Content
MilliporeSigma

I7401

Sigma-Aldrich

Anti-Interleukin-2 antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-IL-2

Slide 1 of 1
Sign Into View Organizational & Contract Pricing

Select a Size

0.1 MG
$551.65

$551.65

List Price$649.00Save 15%
Web-Only Promotion

Available to ship TODAYDetails

A recombinant, preservative-free antibody is available for your target. Try ZRB2431

About This Item

MDL number:
MFCD00675261
UNSPSC Code:
51111800
NACRES:
NA.41

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

goat

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human

technique(s)

immunocytochemistry: suitable
neutralization: suitable
western blot: suitable

UniProt accession no.

P60568

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... IL2(3558)

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
I5395I6784I3392
Anti-Interleukin-2 antibody produced in goat affinity isolated antibody, lyophilized powder

Sigma-Aldrich

I7401

Anti-Interleukin-2 antibody produced in goat

Anti-Interleukin-12 antibody produced in goat IgG fraction of antiserum, lyophilized powder

Sigma-Aldrich

I5395

Anti-Interleukin-12 antibody produced in goat

Monoclonal Anti-Interleukin-2 antibody produced in mouse clone 5334, purified immunoglobulin, lyophilized powder

Sigma-Aldrich

I6784

Monoclonal Anti-Interleukin-2 antibody produced in mouse

Anti-Interleukin-1α antibody produced in goat IgG fraction of antiserum, lyophilized powder

Sigma-Aldrich

I3392

Anti-Interleukin-1α antibody produced in goat

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody form

IgG fraction of antiserum

antibody form

purified immunoglobulin

antibody form

IgG fraction of antiserum

biological source

goat

biological source

goat

biological source

mouse

biological source

goat

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

mouse

technique(s)

immunocytochemistry: suitable, western blot: suitable, neutralization: suitable

technique(s)

neutralization: suitable

technique(s)

flow cytometry: 25 μg/mL, immunohistochemistry: 8-25 μg/mL, neutralization: suitable

technique(s)

indirect ELISA: suitable, neutralization: suitable, western blot: suitable

General description

Interleukin-2 (IL-2) is a cytokine produced by activated T cells in response to antigen stimulation. IL-2 is important for proliferation of lymphocytes, natural killer cells and macrophages and in the differentiation of CD4+ cells into Th1 and Th2 effector cells. It also has a vital role in modulating the expression of the IL-2 receptor and can facilitate B cell growth and differentiation. Anti-Interleukin-2 antibody can be used for neutralizing the bioactivity of recombinant human IL-2 as well as natural human IL-2. It can also be used in immunohistochemistry. Goat anti-Interleukin-2 antibody reacts specifically with recombinant human IL-2. The antibody exhibits less than 10% cross-reactivity with rmIL-2 and rrIL-2.

Immunogen

recombinant human IL-2.

Application

Anti-Interleukin-2 antibody can be used in western blotting and indirect ELISA for detecting recombinant human IL-2.

Biochem/physiol Actions

The antibody will neutralize the biological activity of recombinant and natural human IL-2. The antibody shows <10% cross reactivity with recombinant mouse and rat IL-2.

Physical form

Lyophilized from 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCN7065
MKBZ6822V
SLBG5177V
070M1361
089K1649

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

T A Waldmann et al.
The Journal of experimental medicine, 160(5), 1450-1466 (1984-11-01)
Using anti-Tac, a monoclonal anti-interleukin 2 (IL-2) receptor antibody, we have explored the possibility that certain activated B cells display receptors for IL-2. Resting normal B cells and unselected B cell lines established from normal individuals were Tac antigen negative.
K A Smith et al.
Proceedings of the National Academy of Sciences of the United States of America, 82(3), 864-868 (1985-02-01)
The cell surface density of high-affinity membrane receptors for the T-lymphocytotrophic hormone interleukin 2 (IL-2) determines the rate of T-cell-cycle progression. Since 10-fold greater numbers of IL-2 receptor molecules were found by using a radiolabeled monoclonal antibody reactive with IL-2
B H Nelson et al.
Advances in immunology, 70, 1-81 (1998-10-02)
Studies of the biology of the IL-2 receptor have played a major part in establishing several of the fundamental principles that govern our current understanding of immunology. Chief among these is the contribution made by lymphokines to regulation of the
Katrina K Hoyer et al.
Immunological reviews, 226, 19-28 (2009-01-24)
Interleukin-2 (IL-2) has multiple, sometimes opposing, functions during an inflammatory response. It is a potent inducer of T-cell proliferation and T-helper 1 (Th1) and Th2 effector T-cell differentiation and provides T cells with a long-lasting competitive advantage resulting in the

Related Content

Data Sheet - I7401

Instructions

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service