I7634

Sigma-Aldrich

D-Isoleucine

≥98% (TLC)

Synonym(s):
(2R, 3R)-2-Amino-3-methylpentanoic acid
Linear Formula:
C2H5CH(CH3)CH(NH2)CO2H
CAS Number:
Molecular Weight:
131.17
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.26

Quality Level

assay

≥98% (TLC)

form

powder

application(s)

cell analysis: suitable

impurities

≤10% allo-isomer

color

white

SMILES string

CC[C@@H](C)[C@@H](N)C(O)=O

InChI

1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m1/s1

InChI key

AGPKZVBTJJNPAG-RFZPGFLSSA-N

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Biochem/physiol Actions

D-Isoleucine may be used to help characterize and differentiate various D-amino acid oxidases. D-Isoleucine may be used to differentiate the activities of D- and L-isoleucine in processes such as the induction of pigmentation in B16F0 melanoma cells.

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Masago Ishikawa et al.
Biological & pharmaceutical bulletin, 30(4), 677-681 (2007-04-06)
Amino acids, the building blocks of proteins, play significant roles in numerous physiological events in mammals. As the effects of amino acids on melanogenesis have yet to be demonstrated, the present study was conducted to identify whether amino acids, in...
A Gholizadeh et al.
Biochemistry. Biokhimiia, 74(2), 137-144 (2009-03-10)
D-Amino acid oxidase (DAAO) is an FAD-dependent enzyme that metabolizes D-amino acids in microbes and animals. However, such ability has not been identified in plants so far. We predicted a complete DAAO coding sequence consisting of 1158 bp and encoding...
Molecular aggregation in selected crystalline 1:1 complexes of hydrophobic D- and L-amino acids. IV. The L-phenylalanine series.
Gorbitz CH, Rissanen K, Valkonen A, Husab? A.
Acta Crystallographica Section C, Crystal Structure Communications, 65, 267-272 (2009)
Shouji Takahashi et al.
Journal of biochemistry, 159(3), 371-378 (2015-11-01)
D-Aspartate oxidase (DDO) catalyzes the oxidative deamination of acidic D-amino acids, whereas neutral and basic D-amino acids are substrates of D-amino acid oxidase (DAO). DDO of the yeast Cryptococcus humicola (ChDDO) has much higher substrate specificity to D-aspartate, but the...
Ivan Kashkan et al.
Plants (Basel, Switzerland), 9(7) (2020-07-12)
Rapid progress in plant molecular biology in recent years has uncovered the main players in hormonal pathways and characterized transcriptomic networks associated with hormonal response. However, the role of RNA processing, in particular alternative splicing (AS), remains largely unexplored. Here...

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