Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
K1876
Kanamycin disulfate salt from Streptomyces kanamyceticus
aminoglycoside antibiotic
Synonym(s):
Kanamycin Disulfate Salt, Kanamycin disulfate, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->4))-2-deoxy-D-Streptamine sulfate (1:2) (salt), Kanamycin A, Kanamycin acid sulfate
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$28.50
Estimated to ship onAugust 12, 2025FromMILWAUKEE
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About This Item
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$28.50
Estimated to ship onAugust 12, 2025FromMILWAUKEE
biological source
Streptomyces kanamyceticus
Quality Level
form
powder
potency
~650 μg per mg
impurities
≤4% Kanamycin B
color
white to off-white
solubility
H2O: 10 mg/mL
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
mycobacteria
mycoplasma
mode of action
protein synthesis | interferes
SMILES string
OS(O)(=O)=O.OS(O)(=O)=O.NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
InChI
1S/C18H36N4O11.2H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17;2*1-5(2,3)4/h4-18,23-29H,1-3,19-22H2;2*(H2,1,2,3,4)/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-;;/m1../s1
InChI key
OGTKIXVMLDAMNU-KNQICTBBSA-N
1 of 4
This Item | K4000 | K1637 | K4013 |
|---|---|---|---|
| antibiotic activity spectrum Gram-negative bacteria, mycobacteria, Gram-positive bacteria, mycoplasma | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria, mycobacteria, mycoplasma | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria, mycobacteria, mycoplasma | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria |
| mode of action protein synthesis | interferes | mode of action protein synthesis | interferes | mode of action protein synthesis | interferes | mode of action protein synthesis | interferes |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| form powder | form powder | form powder | form powder |
| solubility H2O: 10 mg/mL | solubility H2O: 50 mg/mL, clear, colorless to faintly yellow | solubility H2O: 10-50 mg/mL (As a stock solution. Stock solutions should be stored at 2-8°C. Stable at 37°C for 5 days.) | solubility - |
| potency ~650 μg per mg | potency ≥750 μg per mg (dry basis) | potency ≥750 μg per mg | potency - |
General description
Application
Biochem/physiol Actions
Mode of Resistance: Aminoglycoside-modifying enzymes (including acetyltransferase, phosphotransferase, nucleotidyltransferase) can alter this antibiotic, preventing its interaction with ribosomes.
Antimicrobial Spectrum: Kanamycin sulfate is effective against gram-negative and gram-postiive bacteria, and mycoplasma.
Caution
Preparation Note
signalword
Danger
hcodes
Hazard Classifications
Repr. 1B
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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How is shipping temperature determined? And how is it related to the product storage temperature?
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdfHelpful?
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