K3250

Kynuramine dihydrobromide

Name: Kynuramine dihydrobromide
Brand: SIGMA
Price: 145 USD
Availability: InStock

monoamine oxidase substrate, fluorogenic, ≥97% (TLC), crystalline

Synonym(s):

3-(2-Aminophenyl)-3-oxopropanamine

Slide 1 of 4

Select a Size

25 MG

$145.00

100 MG

$351.00

250 MG

$680.00

$145.00

Available to ship TODAYDetails

About This Item

Empirical Formula (Hill Notation):

C₉H₁₂N₂O · 2HBr

CAS Number:

304-47-2

Molecular Weight:

326.03

UNSPSC Code:

12352204

PubChem Substance ID:

24896227

NACRES:

NA.32

MDL number:

MFCD00050683

Key Documents

View All Documentation

Product Name

Kynuramine dihydrobromide, crystalline

SMILES string

Br.NCCC(=O)c1ccccc1N

InChI

1S/C9H12N2O.BrH/c10-6-5-9(12)7-3-1-2-4-8(7)11;/h1-4H,5-6,10-11H2;1H

InChI key

YUPVVZSYBUIDQR-UHFFFAOYSA-N

assay

≥97% (TLC)

form

crystalline

solubility

water: 50 mg/mL, clear to slightly hazy

storage temp.

−20°C

Quality Level

100

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item	K3750	H1771	A9657
Sigma-Aldrich K3250 Kynuramine dihydrobromide	Sigma-Aldrich K3750 L-Kynurenine sulfate salt	Sigma-Aldrich H1771 3-Hydroxy-DL-kynurenine	Sigma-Aldrich A9657 DL-Aminoglutethimide
assay ≥97% (TLC)	assay ≥98% (HPLC)	assay ≥98% (TLC)	assay ≥98% (TLC)
solubility water: 50 mg/mL, clear to slightly hazy	solubility -	solubility 1 M HCl: 49.00-51.00 mg/mL, clear to very slightly hazy	solubility H₂O: slightly soluble 0.2 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 1.2 mg/mL, 0.1 M HCl: soluble, acetonitrile: soluble, methanol: soluble
Quality Level 100	Quality Level 200	Quality Level 200	Quality Level 200
form crystalline	form crystalline	form powder	form powder or crystals
storage temp. −20°C	storage temp. −20°C	storage temp. 2-8°C	storage temp. room temp

Application

Kynuramine dihydrobromide has been used as a substrate for monoamine oxidase.[1][2][3]

Biochem/physiol Actions

Kynuramine dihydrobromide is a substrate for the enzyme monoamine oxidase. The end product is the formation of fluorescence detectable 4-hydroxyquinoline (4-HOQ) measured in a fluorescence spectrophotometer at 380 nm.[1]

General description

Substrate for monoamine oxidase

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Chronic dietary mercury exposure causes oxidative stress, brain lesions, and altered behaviour in Atlantic salmon (Salmo salar) parr

Berntssen MHG, et al.

Aquatic Toxicology (Amsterdam, Netherlands), 65(1), 55-72 (2003)

2-Heteroarylidene-1-indanone derivatives as inhibitors of monoamine oxidase.

Magdalena S Nel et al.

Bioorganic chemistry, 69, 20-28 (2016-09-24)

In the present study a series of fifteen 2-heteroarylidene-1-indanone derivatives were synthesised and evaluated as inhibitors of recombinant human monoamine oxidase (MAO) A and B. These compounds are structurally related to series of heterocyclic chalcone derivatives which have previously been

Synergistic antidepressant-like effect of ferulic acid in combination with piperine: involvement of monoaminergic system

Li G, et al.

Metabolic Brain Disease, 30(6), 1505-1514 (2015)

Evidence for the involvement of the noradrenergic system, dopaminergic and imidazoline receptors in the antidepressant-like effect of tramadol in mice

Jesse CR, et al.

Pharmacology, Biochemistry, and Behavior, 95(3), 344-350 (2010)

Isoflavones prevent oxidative stress and inhibit the activity of the enzyme monoamine oxidase in vitro.

Izaviany da Silva Schmitz et al.

Molecular biology reports, 46(2), 2285-2292 (2019-02-14)

Oxidative stress occurs due to an imbalance between antioxidant defenses and pro-oxidant agents in brain. This condition has been associated to the pathogenesis of several brain diseases; therefore, increasing the use of compounds that exert antioxidant activity. Thus, the objective

View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Kynuramine dihydrobromide