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MilliporeSigma

L5139

Sigma-Aldrich

Lycorine hydrochloride

powder, ≥98% (TLC)

Synonym(s):

Licorin hydrochloride, Lychorine chloride, Lycorine HCl

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20 MG
$371.00

$371.00


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20 MG
$371.00

About This Item

Empirical Formula (Hill Notation):
C16H17NO4 · HCl
CAS Number:
Molecular Weight:
323.77
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.77

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$371.00


In StockDetails


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Product Name

Lycorine hydrochloride, ≥98% (TLC), powder

Quality Level

assay

≥98% (TLC)

form

powder

mp

210-212  °C

solubility

ethanol: 10 mg/mL, clear, colorless to very faintly yellow

storage temp.

2-8°C

SMILES string

Cl.O[C@H]1C=C2CCN3Cc4cc5OCOc5cc4[C@H]([C@@H]1O)[C@@H]23

InChI

1S/C16H17NO4.ClH/c18-11-3-8-1-2-17-6-9-4-12-13(21-7-20-12)5-10(9)14(15(8)17)16(11)19;/h3-5,11,14-16,18-19H,1-2,6-7H2;1H/t11-,14-,15+,16+;/m0./s1

InChI key

VUVNTYCHKZBOMV-NVJKKXITSA-N

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This Item
SML3133M4910M6500
assay

≥98% (TLC)

assay

≥95% (HPLC)

assay

≥98% (TLC)

assay

≥98% (titration)

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

300

form

powder

form

powder

form

powder

form

powder or crystals

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

ethanol: 10 mg/mL, clear, colorless to very faintly yellow

solubility

DMSO: 2 mg/mL, clear

solubility

water: 49.00-51.00 mg/mL, clear, colorless to faintly yellow

solubility

water: 50 mg/mL, clear, colorless to very faintly yellow

mp

210-212  °C

mp

-

mp

-

mp

67-71 °C

Biochem/physiol Actions

A selective inhibitor of peptidyl transferase center (PTC).
A selective inhibitor of peptidyl transferase center (PTC). In HL-60 (leukemia) cells, lycorine arrests the cell cycle at G2/M and induces apoptosis by a caspase-mediated pathway.

Caution

Protect from light.

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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