L5163
Latrunculin A
From sea sponge, ≥85% (HPLC), Inhibitor of actin assembly and polymerization, waxy solid
Synonym(s):
LAT-A, [1R-[1R*, 4Z, 8E, 10Z, 12S*, 15R*, 17R*(R*)]]-4-(17-Hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl)-2-thiazolidinone
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
100 μg | Estimated to ship TODAYfromSAINT LOUIS | $406.00 |
About This Item
Product Name
Latrunculin A, from sea sponge, ≥85% (HPLC), waxy solid
biological source
sea sponge
Quality Segment
assay
≥85% (HPLC)
form
waxy solid
mol wt
421.6
solubility
DMSO: soluble, ethanol: soluble
storage temp.
−20°C
SMILES string
C[C@H]1CC[C@@H]2C[C@H](C[C@@](O)(O2)[C@@H]3CSC(=O)N3)OC(=O)C=C(C)CC\C=C\C=C1
InChI
1S/C22H31NO5S/c1-15-7-5-3-4-6-8-16(2)11-20(24)27-18-12-17(10-9-15)28-22(26,13-18)19-14-29-21(25)23-19/h3-5,7,11,15,17-19,26H,6,8-10,12-14H2,1-2H3,(H,23,25)/b4-3+,7-5-,16-11-/t15-,17-,18-,19+,22-/m1/s1
InChI key
DDVBPZROPPMBLW-IZGXTMSKSA-N
General description
Application
Biochem/physiol Actions
1 of 1
This Item | |||
|---|---|---|---|
| description from sea sponge, ≥85% (HPLC), waxy solid | description InSolution | description Latrunculin B, CAS 76343-94-7, is a unique marine toxin that inhibits actin polymerization and disrupts microfilament organization. It is 10 to 100-fold more potent than cytochalasins. | description Latrunculin A, CAS 76343-93-6, is a cell-permeable marine toxin that disrupts microfilament organization in cultured cells by the formation of a 1:1 complex with monomeric G-actin (KD = 200 nM). |
| form waxy solid | form liquid | form solid | form solid |
| assay ≥85% (HPLC) | assay ≥85% (HPLC) | assay ≥95% (HPLC) | assay ≥95% (HPLC) |
| Quality Level 200 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| mol wt 421.6 | mol wt - | mol wt - | mol wt - |
| solubility DMSO: soluble, ethanol: soluble | solubility - | solubility DMSO: 25 mg/mL, ethanol: 25 mg/mL, methanol: 50 mg/mL | solubility DMSO: 25 mg/mL |
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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