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L7007

Sigma-Aldrich

Lysergic acid diethylamide

Synonym(s):

LSD, Lysergide

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About This Item

Empirical Formula (Hill Notation):
C20H25N3O
CAS Number:
50-37-3
Molecular Weight:
323.43
EC Number:
200-033-2
MDL number:
MFCD00135795
UNSPSC Code:
12352106
PubChem Substance ID:
24896390
NACRES:
NA.77

Quality Level

200

drug control

USDEA Schedule I; Home Office Schedule 1; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

storage temp.

−20°C

SMILES string

[H][C@@]12Cc3c[nH]c4cccc(C1=C[C@H](CN2C)C(=O)N(CC)CC)c34

InChI

1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18-/m1/s1

InChI key

VAYOSLLFUXYJDT-RDTXWAMCSA-N

Gene Information

human ... DRD2(1813) , HTR1A(3350) , HTR2A(3356) , HTR2C(3358) , HTR6(3362)
rat ... Htr1a(24473) , Htr2a(29595) , Htr2c(25187) , Htr7(65032)

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Biochem/physiol Actions

Potent hallucinogen; non-selective serotonin receptor agonist.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Carc. 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
0000222595
13150506
0000176486
106M4039V
125M4019V

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Christina Grumann et al.
Journal of pharmaceutical and biomedical analysis, 174, 270-276 (2019-06-11)
A variety of hallucinogens of the lysergamide type has emerged on the drug market in recent years and one such uncontrolled derivative of lysergic acid diethylamide (LSD) is 1-propionyl-LSD (1P-LSD). Due to the high potency of LSD and some of
Differential Classical Conditioning of the Nocebo Effect: Increasing Heat-Pain Perception without Verbal Suggestions.
Anne-Kathrin Bräscher et al.
Frontiers in psychology, 8, 2163-2163 (2018-01-13)
Ingrid Garbus et al.
PloS one, 12(11), e0185595-e0185595 (2017-11-02)
A long-standing goal in plant breeding has been the ability to confer apomixis to agriculturally relevant species, which would require a deeper comprehension of the molecular basis of apomictic regulatory mechanisms. Eragrostis curvula (Schrad.) Nees is a perennial grass that
Desiree Abdurrachim et al.
Cardiovascular research, 113(10), 1148-1160 (2017-05-27)
Heart failure is associated with altered myocardial substrate metabolism and impaired cardiac energetics. Comorbidities like diabetes may influence the metabolic adaptations during heart failure development. We quantified to what extent changes in substrate preference, lipid accumulation, and energy status predict
Mohammad B Habibi Najafi et al.
Food science & nutrition, 7(8), 2684-2691 (2019-08-21)
Instrumental hardness and sensory characteristics of pistachio nuts such as flavor, texture, and overall acceptability were measured in three different packages (atmosphere, vacuum, and oxygen scavenger), at three different conditions temperatures (20, 35, and 50˚C) during 12 weeks' storage. Results showed
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