Anti-Human Lambda Light Chain (Bound and Free) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

MDL number:

biological source


antibody form

IgG fraction of antiserum

antibody product type

secondary antibodies




buffered aqueous solution


indirect ELISA: 1:100,000
quantitative precipitin assay: 3-4 mg/mL



shipped in

dry ice

storage temp.


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Anti-Human λ Light Chain (Bound and Free) antibody produced in rabbit was used to detect free immunoglobulin light chains in sera/plasma of patients with chronic renal failure. It was used as a standard in immunoaffinity columns to isolate λ chains from effluent of patients undergoing continuous ambulatory peritoneal dialysis.

Biochem/physiol Actions

Immunoglobulins (Ig) are produced by the B cells and play crucial role in host humoral immune response. A typical immunoglobulin consists of two heavy chains and two light chains. The two light chains are either κ or the λ chain. The B cells express one type of light chain during their life time.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as preservative


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


NONH for all modes of transport

WGK Germany


Certificate of Analysis
Certificate of Origin
G Cohen et al.
Journal of the American Society of Nephrology : JASN, 6(6), 1592-1599 (1995-12-01)
Circulating plasma factors accumulating in the serum of uremic patients have the potential to inhibit essential functions of polymorphonuclear leukocytes (PMNL). As a consequence, these factors can contribute to the increased risk for bacterial infections generally found in uremic patients....
Gerald Cohen et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 17(5), 879-883 (2002-05-01)
Free immunoglobulin light chains (FLCs) have previously been shown to be uraemic toxins. In this work we investigated the effect of haemodialysis and haemodiafiltration on the level of FLCs in serum/plasma of uraemic patients. Serum/plasma proteins were separated by non-reducing...
Jerry A Katzmann et al.
Clinical chemistry, 48(9), 1437-1444 (2002-08-27)
The detection of monoclonal free light chains (FLCs) is an important diagnostic aid for a variety of monoclonal gammopathies and is especially important in light-chain diseases, such as light-chain myeloma, primary systemic amyloidosis, and light-chain-deposition disease. These diseases are more...

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