L9037

L-Lysine monohydrate

BioReagent, suitable for cell culture, from non-animal source

• Synonym(s): L-Lysine hydrate (1:1), Lysine monohydrate
• Empirical Formula (Hill Notation): C₆H₁₄N₂O₂ · H₂O
• CAS Number: 39665-12-8
• Molecular Weight: 164.20
• Beilstein: 4349963
• EC Number: 200-294-2
• MDL number: MFCD00151035
• PubChem Substance ID: 24896515

Properties

• biological source: non-animal source
• Quality Level: 200
• product line: BioReagent
• Assay: 98.5-101.5% dry basis
• form: crystalline powder
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, tested
• color: white
• mp: 215 °C
• solubility: H₂O: soluble
• SMILES string: [H]O[H].NCCCC[C@H](N)C(O)=O
• InChI: 1S/C6H14N2O2.H2O/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H2/t5-;/m0./s1
• InChI key: HZRUTVAFDWTKGD-JEDNCBNOSA-N

Description

General description

L-Lysine is an amino acid with a basic side chain and is amphipathic in nature. It has a protonated alkyl amino group and is fully protonated at physiological pH. L-lysine mainly participates in electrostatic interactions in proteins.

Application

L-Lysine monohydrate has been used in:

• SILAC (stable isotope labeling by amino acids in cell culture) method
• the complete synthetic (C) medium for positive selection screening of yeast cells
• the growth medium for cells

Biochem/physiol Actions

L-Lysine is an essential proteinogenic α amino acid used in a wide range of applications including as a non-animal sourced supplement in cell culture media, a substrate of enzymes such as L-lysine oxidase (EC 1.4.3.14), a component of poly-lysine polymers, and a substrate for oxidation and glycation mechanism studies.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves