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L9634

Sigma-Aldrich

Laminarin from Laminaria digitata

polysaccharide substrate for laminarinase

Synonym(s):
Laminaran
CAS Number:
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

biological source

algae (Laminaria digitata)

Quality Level

form

powder

optical activity

[α]20/D -20 to -5 °, c = 4% (w/v) in water

InChI

1S/C18H32O16/c19-1-4-7(22)10(25)11(26)17(31-4)34-15-9(24)6(3-21)32-18(13(15)28)33-14-8(23)5(2-20)30-16(29)12(14)27/h4-29H,1-3H2/t4-,5-,6-,7-,8-,9-,10+,11-,12-,13-,14+,15+,16?,17?,18?/m1/s1

InChI key

DBTMGCOVALSLOR-VPNXCSTESA-N

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General description

The fronds of Laminaria and Saccharina species contain laminarin, a low molecular weight storage glucan. It is localized to the vacuoles. Laminarin structure contains β-(1,6)-intrachain linked (1,3)-β-d-glucan.

Application

Laminarin from Laminaria digitata has been used:
  • as a stimulant to study its effect on the respiratory burst using haemocytes of P. vannamei
  • as a carbon source to study its effect on enzyme production using Pichia membranifaciens culture
  • as a carbon source for Polaribacter sp. culture

Packaging

100, 500 mg in poly bottle
1, 5 g in poly bottle

Biochem/physiol Actions

Laminarin is a polysaccharide of glucose found in brown algae and utilized as a food reserve.
Laminarin is a biologically active compound effective against inflammation. It serves as an antioxidant and anticoagulant. Laminarin also inhibits apoptosis and tumor development. It acts as a predominant source of carbon among aquatic prokaryotes.

Other Notes

Polysaccharide; primarily poly(β-Glc-[1→3]) with some β-(1→6) interstrand linkages and branch points.

Substrates

Substrate for laminarinase.

Storage Class Code

11 - Combustible Solids

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

  1. How does the storage temperature relate to shipping conditions?

    The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment. See Shipping and Storage for more information.

  2. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  3. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  4. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  5. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  6. What is the exact molecular weight (MW) of Product L9634, Laminarin?

    Product L9634, Laminarin, is a mixture of different carbohydrates of different MW values.  One publication has done a detailed ESI-MS analysis of laminarin from Laminaria digitata.  Read, S.M., et al., Analysis of the structural heterogeneity of laminarin by electrospray-ionisation-mass spectrometry.  Carbohydrate Res., 281(2), 187-201 (1996). 

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    Ask a Scientist here.

Choa An et al.
Applied and environmental microbiology, 79(3), 860-866 (2012-11-28)
Edible brown algae are used as major food material in Far East Asian countries, particularly in South Korea and Japan. They contain fermentable dietary fibers, alginic acid (uronic acid polymer) and laminaran (β-1,3-glucan), that are fermented into organic acids by...
Extraction, structure and biofunctional activities of laminarin from brown algae
Kadam SU, et al.
International Journal of Food Science and Technology, 50(1), 24-31 (2015)
Jeannette Vera et al.
Marine drugs, 9(12), 2514-2525 (2012-03-01)
Plants interact with the environment by sensing "non-self" molecules called elicitors derived from pathogens or other sources. These molecules bind to specific receptors located in the plasma membrane and trigger defense responses leading to protection against pathogens. In particular, it...
Niches of two polysaccharide-degrading Polaribacter isolates from the North Sea during a spring diatom bloom
Xing P, et al.
The ISME Journal, 9(6), 1410-1410 (2015)
Tomasz Lipinski et al.
Journal of immunology (Baltimore, Md. : 1950), 190(8), 4116-4128 (2013-03-22)
In a previous attempt to generate a protective vaccine against Candida albicans, a β-mannan tetanus toxoid conjugate showed poor immunogenicity in mice. To improve the specific activation toward the fungal pathogen, we aimed to target Dectin-1, a pattern-recognition receptor expressed...

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