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MilliporeSigma

L9650

Lithium chloride

Molecular Biology, ≥99%

Synonym(s):

LiCl

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100 G

$66.60

500 G

$197.00

$66.60


Estimated to ship onDecember 15, 2025Details


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About This Item

Linear Formula:
LiCl
CAS Number:
Molecular Weight:
42.39
EC Number:
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.31
Assay:
≥99%
Grade:
Molecular Biology
Form:
powder
Solubility:
H2O: 100 mg/mL at 20 °C, clear, colorless

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grade

Molecular Biology

Quality Level

assay

≥99%

form

powder

mp

605 °C (lit.)

solubility

H2O: 100 mg/mL at 20 °C, clear, colorless

anion traces

sulfate (SO42-): ≤0.01%

cation traces

Ba: ≤0.003%
Fe: ≤0.001%
K: ≤0.01%
Na: ≤0.20%
heavy metals (as Pb): ≤0.002%

foreign activity

DNase, NICKase, RNase, protease, none detected

SMILES string

[Li+].[Cl-]

InChI

1S/ClH.Li/h1H;/q;+1/p-1

InChI key

KWGKDLIKAYFUFQ-UHFFFAOYSA-M

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Show Differences

1 of 4

This Item
62476L4408213233
form

powder

form

powder or crystals

form

powder

form

powder, crystals or granules

assay

≥99%

assay

≥99.0% (AT)

assay

≥99.0% (titration)

assay

99%

solubility

H2O: 100 mg/mL at 20 °C, clear, colorless

solubility

H2O: 1 M at 20 °C, clear, colorless

solubility

H2O: 1 M, clear, colorless

solubility

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

grade

for molecular biology

grade

for molecular biology

grade

-

grade

-

anion traces

sulfate (SO42-): ≤0.01%

anion traces

sulfate (SO42-): ≤50 mg/kg

anion traces

sulfate (SO42-): ≤0.01%

anion traces

-

Application

Lithium chloride has been used:
  • in the preparation of wash buffer for chromatin immunoprecipitation[1]
  • in 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay[2]
  • to treat aged myoblast as glycogen synthase kinase (GSK) inhibitor to analyse its effect on wingless/tailess (wnt) signaling[3]

May be used to selectively pre­cipitate RNA.

Biochem/physiol Actions

Lithium chloride has the ability to block glycogen synthase kinase (GSK). It may also possess anti-inflammatory effects at low and non-toxic concentrations.[4]

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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mTOR and neuroinflammation
Molecules to Medicine with mTOR, 317-329 (2016)
A laboratory practical illustrating the use of the ChIP-qPCR method in a robust model: Estrogen receptor alpha immunoprecipitation using Mcf-7 culture cells
Lacazette E
Biochemistry and Molecular Biology Education, 45(2), 152-160 (2017)
Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts
Vertino AM, et al.
Molecular Biology of the Cell, 16(4), 2039-2048 (2005)
Laforin negatively regulates cell cycle progression through glycogen synthase kinase 3beta-dependent mechanisms
Liu R, et al.
Molecular and cellular biology, 28(23), 7236-7244 (2008)
Alessandro Di Maio et al.
EvoDevo, 6, 17-17 (2015-07-15)
Wnt signaling is one of the earliest and most highly conserved regulatory pathways for the establishment of the body axes during regeneration and early development. In regeneration, body axes determination occurs independently of tissue rearrangement and early developmental cues. Modulation

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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