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LO1280

Sigma-Aldrich

LOPAC®1280

Synonym(s):
Library of Pharmacologically Active Compounds

form

liquid

Quality Level

shipped in

dry ice

storage temp.

−20°C

General description

Compounds are arranged in 96-well format in 16 racks of 80, one compound per well (250 μl at 10 mM in DMSO).

Application

LOPAC®1280 has been used:
  • in the screening of novel inhibitors for chemotaxis/ migration using Dictyostelium as a model
  • to test the ability to modulate and to measure forskolin-stimulated cAMP levels in CHO-hCB2 cells and to modulate ligand-induced receptor/β-arrestin interaction
  • in screening of small molecules for activating bone morphogenetic protein (BMP) signaling
  • in screening of compounds that plays a role in regulating subcellular localization of nitric oxide associated protein 1 (NOA1) protein

Features and Benefits

Includes the latest, drug-like molecules in the fields of Cell Signaling & Neuroscience:

  • Apoptosis
  • G Proteins & Cyclic Nucleotides
  • Gene Regulation & Expression
  • Ion Channels
  • Lipid Signaling
  • Multi-Drug Resistance
  • Neurotransmission
  • Phosphorylation
SDFile provided to construct a database containing:
  • Structure
  • Primary Name
  • Secondary Name
  • Pharmacological Activity
  • Product Number
  • Rack Position
Collection of 1,280 Pharmacologically-Active Sigma Compounds
To request a list of components, please visit sigma.com/LOPAC

Other Notes

For sale in the U.S. only. Customers outside of the U.S. should refer to product code LO3300.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Signal Word

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Lact. - Muta. 1B - Repr. 1A - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 2

Storage Class Code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

188.6 °F - closed cup

Flash Point(C)

87 °C - closed cup

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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