M0252

All Photos(1)

M0252

Methylglyoxal solution

~40% in H₂O

All Photos(1)

Synonym(s):

Acetylformaldehyde, Pyruvaldehyde, Pyruvic aldehyde

Linear Formula:

CH₃COCHO

CAS Number:

78-98-8

Molecular Weight:

72.06

Beilstein:

906750

MDL number:

MFCD00006960

PubChem Substance ID:

24896540

NACRES:

NA.32

Assay

~40% (enzymatic)

Quality Level

200

form

liquid

concentration

~40% in H₂O

density

1.17 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

[H]C(=O)C(C)=O

InChI

1S/C3H4O2/c1-3(5)2-4/h2H,1H3

InChI key

AIJULSRZWUXGPQ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

1 of 4

This Item	67028	128465	50649
Sigma-Aldrich M0252 Methylglyoxal solution	Sigma-Aldrich 67028 Methylglyoxal solution	Sigma-Aldrich 128465 Glyoxal solution	Sigma-Aldrich 50649 Glyoxal solution
assay ~40% (enzymatic)	assay -	assay -	assay -
form liquid	form -	form liquid	form liquid
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. -	storage temp. 2-8°C
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 100
concentration ~40% in H₂O	concentration ~40% in H₂O	concentration 40 wt. % in H₂O	concentration ~40% in H₂O (~8.8 M)
density 1.17 g/mL at 25 °C (lit.)	density 1.19 g/mL at 20 °C	density 1.265 g/mL at 25 °C	density -

General description

Methylglyoxal (MG) is a glucose metabolite, which is linked to peripheral neuropathy and pain in diabetic patients. It enhances intracellular calcium in sensory neurons and produces behavioral nociception. Methylglyoxal has antibacterial property. MG functions as a protein-glycating agent and precursor of advanced glycation end products. It impairs diabetic wound healing.

Application

Methylglyoxal solution has been used:

to assess glyoxalase 1 (GLO1) enzymatic activity
as an advanced glycation end (AGE) forming agent for the preparation of albumin in vitro
to regulate anxiety like behavior in mice
to induce peritoneal fibrosis in rats
to study the chromatographic retention characteristics of organic chemicals and metal DNA adducts
for intraplantar injection in mice to investigate peripheral and central components of methylglyoxal (MG)-transient receptor potential ankyrin 1 (TRPA1)-adenylyl cyclase 1 isoform (AC1) pathway

Pictograms

GHS05,GHS07,GHS08

Signal Word

Danger

Hazard Statements

H290 - H317 - H318 - H341

Precautionary Statements

P202 - P234 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Muta. 2 - Skin Sens. 1

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Methylglyoxal solution

~40% in H₂O