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M0388

6α-Methyl-11β-hydroxyprogesterone

Synonym(s):

11β-Hydroxy-6α-methyl-4-pregnene-3,20-dione, Medrysone

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250 MG

$83.20

$83.20

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About This Item

Empirical Formula (Hill Notation):
C22H32O3
CAS Number:
2668-66-8
Molecular Weight:
344.49
NACRES:
NA.77
PubChem Substance ID:
24896551
UNSPSC Code:
12352200
EC Number:
220-208-7
MDL number:
MFCD00056477

Key Documents

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InChI key

GZENKSODFLBBHQ-ILSZZQPISA-N

InChI

1S/C22H32O3/c1-12-9-15-17-6-5-16(13(2)23)22(17,4)11-19(25)20(15)21(3)8-7-14(24)10-18(12)21/h10,12,15-17,19-20,25H,5-9,11H2,1-4H3/t12-,15-,16+,17-,19-,20+,21-,22+/m0/s1

SMILES string

[H][C@@]12C[C@H](C)C3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@]4(C)[C@H](CC[C@@]24[H])C(C)=O

sterility

non-sterile

form

solid

shipped in

ambient

storage temp.

2-8°C

Quality Level

200

Gene Information

human ... NR3C1(2908)

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Show Differences

1 of 4

This Item
M0639M1629P0130
6α-Methyl-11β-hydroxyprogesterone

Sigma-Aldrich

M0388

6α-Methyl-11β-hydroxyprogesterone

6α-Methylprednisolone ≥98%

Sigma-Aldrich

M0639

6α-Methylprednisolone

Medroxyprogesterone 17-acetate ≥97% (HPLC)

Sigma-Aldrich

M1629

Medroxyprogesterone 17-acetate

Progesterone ≥99%

Sigma-Aldrich

P0130

Progesterone

form

solid

form

powder

form

powder

form

powder

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200

storage temp.

2-8°C

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

shipped in

ambient

shipped in

ambient

shipped in

ambient

shipped in

ambient

sterility

non-sterile

sterility

non-sterile

sterility

non-sterile

sterility

non-sterile

Gene Information

human ... NR3C1(2908)

Gene Information

human ... NR3C1(2908)
rat ... Nr3c1(24413)

Gene Information

human ... AR(367), ESR1(2099), ESRRA(2101), NR3C1(2908), NR3C2(4306), PGR(5241)
rat ... Ar(24208)

Gene Information

human ... ABCB1(5243), AR(367), CYP2C9(1559), EBP(10682), ESR1(2099), ESR2(2100), NR3C1(2908), NR3C2(4306), PGR(5241), SERPINA6(866)
mouse ... Esr1(13982)
rat ... Ar(24208), Nr3c1(24413), Pgr(25154)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
058F0271
058F02711

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Management of vernal conjunctivitis with steroid induced glaucoma--a comparative study.
S Mithal et al.
Indian journal of ophthalmology, 35(5-6), 298-301 (1987-01-01)
N L Verbey et al.
Current eye research, 7(6), 557-561 (1988-06-01)
The effect of topical administration of 3-isobutyl-methyl-xanthine (IBMX), a potent phosphodiesterase inhibitor, was studied on an experimentally provoked uveitis in rabbits. After presensitization with an intravitreal injection of human serum albumin (HSA), intravenous antigenic challenge induces blood-aqueous barrier breakdown and
Ocular pemphigus.
I A Abboud et al.
The Journal of the Egyptian Medical Association, 61(7-8), 511-522 (1978-01-01)
Nuclear translocation of the cytoplasmic glucocorticoid receptor in the iris-ciliary body and adjacent corneoscleral tissue of the rabbit following topical administration of various glucocorticoids. A rapid screening method for glucocorticoid activity.
A L Southren et al.
Investigative ophthalmology & visual science, 24(2), 147-152 (1983-02-01)
J F Recasens et al.
Ophthalmic research, 22(1), 12-18 (1990-01-01)
Superoxide dismutase activity (SOD) was measured in the irides of control animals and 24 h after the intravitreal administration of Escherichia coli endotoxin. A 3-fold increase in SOD was noted (p less than 0.001). To protect against the inflammatory process
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