M046030

Cyanine 5 Phosphoramidite

configured for ABI ÄKTA^® and OligoPilot^®

• Synonym(s): 2-[5-[1,3-Dihydro-1-[3-(4-methoxytriphenylmethoxy)propyl]-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1-[3-[N,N-diisopropylamino(2-cyanoethoxy)phosphinoxy]propyl]-3,3-dimethyl-3H-indolium
• Empirical Formula (Hill Notation): C₆₀H₇₂N₄O₄P
• CAS Number: 351186-76-0
• Molecular Weight: 944.21
• UNSPSC Code: 41116105
• PubChem Substance ID: 329817793
• NACRES: NA.21
• Assay: (reversed phase HPLC), ≥90% (³¹P-NMR)
• Form: solid
• Solubility: acetonitrile: 0.1 M, clear, blue
• Storage temp.: −20°C

Properties

• product line: Proligo Reagents
• Quality Segment: 200
• assay: (reversed phase HPLC), ≥90% (³¹P-NMR)
• form: solid
• mol wt: 944.21 g/mol
• color: clear blue0.1M in Acetonitrile
• solubility: acetonitrile: 0.1 M, clear, blue
• compatibility: configured for ABI ÄKTA^® and OligoPilot^®
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: CC(C1=C(N/2CCCOP(N(C(C)C)C(C)C)OCCC#N)C=CC=C1)(C)C2=C\C=C\C=C\C(C3(C)C)=[N+](CCCOC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)C7=C3C=CC=C7.[Cl-]
• InChI: 1S/C60H72N4O4P.ClH/c1-46(2)64(47(3)4)69(67-44-23-40-61)68-45-25-42-63-55-33-22-20-31-53(55)59(7,8)57(63)35-18-12-17-34-56-58(5,6)52-30-19-21-32-54(52)62(56)41-24-43-66-60(48-26-13-10-14-27-48,49-28-15-11-16-29-49)50-36-38-51(65-9)39-37-50;/h10-22,26-39,46-47H,23-25,41-45H2,1-9H3;1H/q+1;/p-1
• InChI key: GWCNEDQILVVBDJ-UHFFFAOYSA-M

Description

General description

Phosphoramidite technology is ideally suited for the modification ofsynthetic oligonucleotides with covalently attached reporter moieties,linkers, spacers, or haptens. Sigma-Aldrich provides popular reporters andlinkers ready to use for DNA/RNA synthesis machines such as β-cyanoethylphosphoramidites. Cyanine 5 Phosphoramidite is one such label whose absorbance maxima is 646 nm and emission maxima is 662nm.Cyanine 5 Phosphoramidite is configured for ABI^™ Synthesizers.

Legal Information

ABI is a trademark of Applera Corporation or its subsidiaries in the US and/or certain other countries

OligoPilot is a registered trademark of Cytiva

ÄKTA is a registered trademark of Cytiva

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable