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MilliporeSigma

M1520

IgM, Kappa from murine myeloma

clone TEPC 183, ascites fluid, lyophilized powder

Synonym(s):

Mouse IgM-κ

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
MFCD00283897
Conjugate:
unconjugated
Clone:
TEPC 183, monoclonal
Application:
—
Citations:
7

Key Documents

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biological source

mouse

conjugate

unconjugated

antibody form

ascites fluid

clone

TEPC 183, monoclonal

form

lyophilized powder

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

200

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This Item
M3795SAB4200857M9035
IgM, Kappa from murine myeloma clone TEPC 183, ascites fluid, lyophilized powder

Sigma-Aldrich

M1520

IgM, Kappa from murine myeloma

IgM, Kappa from murine myeloma clone TEPC 183, purified immunoglobulin, buffered aqueous solution

Sigma-Aldrich

M3795

IgM, Kappa from murine myeloma

IgM, Kappa from murine myeloma clone TEPC 183-SY, purified from hybridoma cell culture

Sigma-Aldrich

SAB4200857

IgM, Kappa from murine myeloma

IgG1, Kappa from murine myeloma clone MOPC 31C, purified immunoglobulin, buffered aqueous solution

Sigma-Aldrich

M9035

IgG1, Kappa from murine myeloma

biological source

mouse

biological source

mouse

biological source

-

biological source

mouse

antibody form

ascites fluid

antibody form

purified immunoglobulin

antibody form

purified from hybridoma cell culture

antibody form

purified immunoglobulin

conjugate

unconjugated

conjugate

unconjugated

conjugate

-

conjugate

unconjugated

clone

TEPC 183, monoclonal

clone

TEPC 183, monoclonal

clone

TEPC 183-SY

clone

MOPC 31C, monoclonal

Quality Level

200

Quality Level

300

Quality Level

300

Quality Level

200

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

General description

The TEPC-183 tumor line that produces mouse IgM is a tetramethylpentadecane (pristane) induced plasmacytoma, originated and carried intraperitoneally in BALB/c mice. Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE.[1] IgM is present on the surface of B lymphocytes in its monomeric form.[2]

Application

IgM, Kappa from murine myeloma has been used as a control to study its effects on brain derived synaptic plasticity.[3]

Biochem/physiol Actions

IgM antibodies are present as pentamers in serum and are produced in response to antigens.[4]

Preparation Note

Reconstitute with 1 ml deionized water.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
069M4882V
069M4882V
027M4808V
061M4799V
048K4873

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A monoclonal antibody against synthetic A beta dimer assemblies neutralizes brain-derived synaptic plasticity-disrupting A beta
ONuallain B, et al.
Journal of Neurochemistry, 119(1), 189-201 (2011)
Molecular Genetics of Immunoglobulin, 17 (1987)
M Lohoff et al.
Infection and immunity, 56(8), 2120-2124 (1988-08-01)
The well-established polyclonal B-cell stimulation in the lymphoid organs in mice infected with Leishmania major is thought to be dependent on T cells. Here we present clear experimental evidence that this is indeed the case by showing that BALB/c-derived, L3T4-positive
Brian O'Nuallain et al.
Journal of neurochemistry, 119(1), 189-201 (2011-07-26)
Diverse lines of evidence indicate that pre-fibrillar, diffusible assemblies of the amyloid β-protein (Aβ) play an important role in Alzheimer's disease pathogenesis. Although the precise molecular identity of these soluble toxins remains unsettled, recent experiments suggest that sodium dodecyl sulfate
The Immunoglobulins: Structure and Function (1998)
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