MilliporeSigma
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M2521

Sigma-Aldrich

IgM, Lambda from murine myeloma

clone MOPC 104E, ascites fluid, lyophilized powder

Synonym(s):
Mouse IgM-λ
MDL number:
NACRES:
NA.46

biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

ascites fluid

clone

MOPC 104E, monoclonal

form

lyophilized powder

storage temp.

2-8°C

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This Item
I4765SCC429270A-1
conjugate

unconjugated

conjugate

unconjugated

conjugate

-

conjugate

unconjugated

antibody form

ascites fluid

antibody form

purified immunoglobulin

antibody form

-

antibody form

Ig fraction of antiserum

clone

MOPC 104E, monoclonal

clone

-

clone

-

clone

polyclonal

form

lyophilized powder

form

-

form

-

form

buffered aqueous solution

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−196°C

storage temp.

2-8°C

General description

The MOPC-104E tumor line that produces mouse IgM is a mineral oil induced plasmacytoma originated and carried intraperitoneally in BALB/c mice. Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. IgM is present on the surface of B lymphocytes in its monomeric form.

Specificity

Antigen Specificity: α(1→3) glucose

Application

IgM, λ from murine myeloma has been used as control in chromatin immunoprecipitation analysis. It has also been used in immunohistochemitsry.
IgM, λ from murine myeloma was used as a control antibody in ChIP analysis of GATA-1-null and GATA-1-positive G1E cells.

Biochem/physiol Actions

IgM antibodies are present as pentamers in the serum and are produced in response to antigens.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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25G
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GATA-1-mediated Transcriptional Repression Yields Persistent Transcription Factor IIB-Chromatin Complexes
Martowicz ML, et al.
The Journal of biological chemistry, 281(49), 37345-37352 (2006)
D Chen et al.
The American journal of physiology, 277(3), H1100-H1106 (1999-09-14)
Abnormal proliferation of vascular smooth muscle cells (VSMCs) is thought to play an important role in the pathogenesis of atherosclerosis and restenosis. Previous studies have implicated the extracellular matrix protein thrombospondin-1 (TSP1) in mitogen-dependent proliferation of VSMCs. In this study
Molecular Genetics of Immunoglobulin, 17 (1987)
Endosomal/Lysosomal Processing of Gangliosides Affects Neuronal Cholesterol Sequestration in Niemann-Pick Disease Type C
Zhou S, et al.
The American Journal of Pathology, 179(2), 890-902 (2011)
Robert McGlynn et al.
The Journal of comparative neurology, 480(4), 415-426 (2004-11-24)
The mucopolysaccharidoses (MPSs) are a complex family of lysosomal storage disorders characterized by failure to degrade heparan sulfate (HS) and/or other types of glycosaminoglycans (GAGs) secondary to the absence of specific lysosomal enzymes. An accompanying storage of glycosphingolipids (GSLs), most

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