M5170

IgM, Lambda from murine myeloma

clone MOPC 104E, purified immunoglobulin, buffered aqueous solution

• Synonym(s): Mouse IgM-λ
• MDL number: MFCD00164805
• UNSPSC Code: 12352203
• NACRES: NA.46

Properties

• biological source: mouse
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• clone: MOPC 104E, monoclonal
• form: buffered aqueous solution
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified

Description

General description

IgM antibodies are present as pentamers in the serum and are produced in response to antigens[1]
IgM, λ from murine myeloma is produced by MOPC 104E tumor line introduced subcutaneously in BALB/c mice. It specifically recognizes mouse IgM, λ. Identity and purity of the immunoglobulin is established by immunoelectrophoresis.

Specificity

Antigen Specificity: α(1→3) glucose

Application

IgM, λ from murine myeloma was used as standard in ELISA[2] and as isotype control in immunohistochemistry applications.[3]

Biochem/physiol Actions

IgM antibodies are produced initially during B-cell development. IgM participates in opsonization and compliment fixation. Defect in IgM production is observed in X-linked agammaglobulinemia.[4]

Physical form

Solution in 0.05 M Tris, 0.5 M sodium chloride, pH 8.0, containing 0.02% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable