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MilliporeSigma

M6514

3-(Trimethoxysilyl)propyl methacrylate

≥97%

Synonym(s):

Silane A174, [3-(Methacryloyloxy)propyl]trimethoxysilane

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25 ML

$72.90

50 ML

$111.00

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About This Item

Linear Formula:
H2C=C(CH3)CO2(CH2)3Si(OCH3)3
CAS Number:
Molecular Weight:
248.35
UNSPSC Code:
47101511
NACRES:
NA.56
PubChem Substance ID:
EC Number:
219-785-8
Beilstein/REAXYS Number:
1952435
MDL number:

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InChI key

XDLMVUHYZWKMMD-UHFFFAOYSA-N

InChI

1S/C10H20O5Si/c1-9(2)10(11)15-7-6-8-16(12-3,13-4)14-5/h1,6-8H2,2-5H3

SMILES string

CO[Si](CCCOC(=O)C(C)=C)(OC)OC

assay

≥97%

form

liquid

refractive index

n20/D 1.431 (lit.)

bp

190 °C (lit.)

density

1.045 g/mL at 25 °C (lit.)

storage temp.

2-8°C

Quality Level

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This Item
440159475149446130
assay

≥97%

assay

98%

assay

92%

assay

98%

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

density

1.045 g/mL at 25 °C (lit.)

density

1.045 g/mL at 25 °C (lit.)

density

1.055 g/mL at 25 °C (lit.)

density

0.918 g/mL at 25 °C (lit.)

refractive index

n20/D 1.431 (lit.)

refractive index

n20/D 1.431 (lit.)

refractive index

n20/D 1.429 (lit.)

refractive index

n20/D 1.419 (lit.)

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

-

bp

190 °C (lit.)

bp

190 °C (lit.)

bp

68 °C/0.4 mmHg (lit.)

bp

112-115 °C/0.2 mmHg (lit.)

General description

3-(Trimethoxysilyl)propyl methacrylate (TMSPMA) is a hydrophobic monomer.[1] The presence of an additional functional group of acrylate facilitates TMSPMA for grafting polymerization on plastic surfaces.[2] 3-(Trimethoxysilyl)propyl methacrylate undergoes first-order kinetic polymerization to form polyTMSPMA, which is a moisture stable polymer.[3]

Application

3-(Trimethoxysilyl)propyl methacrylate has been used in the following applications:
  • Isoelectric focusing can lead to pH gradient formation resulting in the swelling or shrinking of gel casts. This can be prevented by using 3-(Trimethoxysilyl)propyl methacrylate to link polyacrylamide gels to glass plates covalently.[4]
  • In situ hybridization using 3-(Trimethoxysilyl)propyl methacrylate along with poly-L-lysine is a faster and durable method to attach cells, microscopic sections, and total organs to slides/other glass surfaces.[5]
  • 3-(Trimethoxysilyl)propyl methacrylate is also used in the preparation of organic/inorganic hybrid nanomaterials.[6]

Packaging

A product Information sheet is supplied which describes procedures for using this product.

related product

Product No.
Description
Pricing

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

197.6 °F - closed cup

flash_point_c

92 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Preparation of organic/inorganic hybrid nanomaterials using aggregates of poly (stearyl methacrylate)-b-poly (3-(trimethoxysilyl) propyl methacrylate) as precursor.
Junfeng Zhou.
Eur. Polymer J., 5, 1736-1743 (2007)
Improvements of DNA sequencing gels.
H Garoff et al.
Analytical biochemistry, 115(2), 450-457 (1981-08-01)
Saisneha Koppaka et al.
Micromachines, 12(9) (2021-09-29)
Micro-blade design is an important factor in the cutting of single cells and other biological structures. This paper describes the fabrication process of three-dimensional (3D) micro-blades for the cutting of single cells in a microfluidic "guillotine" intended for fundamental wound
Sean Brahim et al.
Biomacromolecules, 4(5), 1224-1231 (2003-09-10)
An amphiphilic hydrogel of poly(2-hydroxyethyl methacrylate) cross-linked with tetraethyleneglycol diacrylate (TEGDA) was synthesized to contain the hydrophobic monomer 3-(trimethoxy-silyl) propyl methacrylate (PMA) and the pH-responsive, hydrophilic monomer N',N'-dimethylaminoethyl methacrylate (DMAEMA). The gels were separately loaded with two biomolecular probes, insulin
ATRP of 3-(triethoxysilyl)propyl methacrylate and preparation of ?stable? gelable block copolymers
Ming Xiong
European Polymer Journal, 44, 3835-3841 (2008)

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Questions

  1. How stable is this product? How many years will it be good if kept at 2 degrees C?

    1 answer
    1. The product remains active for at least 2 years. This product will react with water since alkylsilanes react with hydroxyl groups. An ethanol solution remains active for one day. For more information please see this data sheet: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/139/774/m6514pis.pdf.

      The product specification sheet for this product contains a recommended retest date period of two years after the quality release date. A recommended retest date is the period of time during which the product is expected to remain within established stability specifications, provided that it has been stored under defined conditions. After the Retest Date, product samples should be examined to ensure that the product is still in compliance with the established specifications. For more information, you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/US/en/life-science/quality-and-regulatory-management/quality-services.

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