MilliporeSigma
All Photos(2)

Documents

M7510

Sigma-Aldrich

β,γ-Methyleneadenosine 5′-triphosphate disodium salt

≥95%, solid

Sign Into View Organizational & Contract Pricing

Synonym(s):
AMP-PCP disodium salt, Adenylylmethylenediphosphonate disodium salt
Empirical Formula (Hill Notation):
C11H16N5Na2O12P3
CAS Number:
Molecular Weight:
549.17
PubChem Substance ID:
NACRES:
NA.77

Quality Level

assay

≥95%

form

solid

color

white

solubility

H2O: 10 mg/mL

storage temp.

−20°C

SMILES string

[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)CP(O)([O-])=O)[C@@H](O)[C@H]3O

InChI

1S/C11H18N5O12P3.2Na/c12-9-6-10(14-2-13-9)16(3-15-6)11-8(18)7(17)5(27-11)1-26-31(24,25)28-30(22,23)4-29(19,20)21;;/h2-3,5,7-8,11,17-18H,1,4H2,(H,22,23)(H,24,25)(H2,12,13,14)(H2,19,20,21);;/q;2*+1/p-2/t5-,7-,8-,11-;;/m1../s1

InChI key

KZCUOVRMGTZINH-LYYWGVPGSA-L

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
D0260A6885M6517
assay

≥95%

assay

≥97% (HPLC)

assay

≥98.0% (HPLC)

assay

≥93% (HPLC)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

solubility

H2O: 10 mg/mL

solubility

H2O: 100 mg/mL

solubility

H2O: 10 mg/mL

solubility

H2O: 100 mg/mL

color

white

color

white

color

white

color

white

Application

β,γ-Methyleneadenosine 5′-triphosphate disodium salt has been used as an internal standard for the UDP-hexose analysis with ion pairing high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS).

Biochem/physiol Actions

Selective P2X purinoceptor agonist that is more potent than ATP, but less potent than α, β-methylene-L-adenosine 5′-triphosphate.

Features and Benefits

This compound is featured on the P2 Receptors: P2X Ion Channel Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Physical form

hygroscopic solid

pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Trezise, D.J., et al.
Naunyn-Schmiedeberg'S Archives of Pharmacology, 35, 603-603 (1995)
O'Connor, S.E., et al.
British Journal of Pharmacology, 10, 640-640 (1990)
Mannose inhibits hyaluronan synthesis by down-regulation of the cellular pool of UDP-N-acetylhexosamines
Jokela TA, et al.
The Journal of Biological Chemistry, 283(12), 7666-7673 (2008)
Tony DeFalco et al.
Developmental biology, 352(1), 14-26 (2011-01-25)
During the differentiation of the mammalian embryonic testis, two compartments are defined: the testis cords and the interstitium. The testis cords give rise to the adult seminiferous tubules, whereas steroidogenic Leydig cells and other less well characterized cell types differentiate
Fabian A Grimm et al.
Regulatory toxicology and pharmacology : RTP, 101, 91-102 (2018-11-25)
High-content screening data derived from physiologically-relevant in vitro models promise to improve confidence in data-integrative groupings for read-across in human health safety assessments. The biological data-based read-across concept is especially applicable to bioactive chemicals with defined mechanisms of toxicity; however

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service