MilliporeSigma
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M7765

Sigma-Aldrich

1-Oleoyl-rac-glycerol

≥99%

Synonym(s):
MG(18:1(9Z)/0:0/0:0)[rac], DL-α-Monoolein, Glyceryl cis-9-octadecenoate, Monoolein, 1-(cis-9-Octadecenoyl)-rac-glycerol, rac-Glycerol 1-monooleate
Linear Formula:
CH3(CH2)7CH=CH(CH2)7COOCH2CHOHCH2OH
CAS Number:
Molecular Weight:
356.54
Beilstein:
1728976
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

biological source

synthetic (organic)

description

non-ionic

assay

≥99%

form

powder

mp

35 °C

functional group

ester

shipped in

wet ice

storage temp.

−20°C

SMILES string

CCCCCCCC\C=C/CCCCCCCC(=O)OCC(O)CO

InChI

1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-

InChI key

RZRNAYUHWVFMIP-KTKRTIGZSA-N

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General description

1-Oleoyl-rac-glycerol is a monoglyceride, obtained from natural oils and fats. It contains two alcohol groups that are reactive. It is soluble in chloroform and hexane. It can be crystallized from hexane.

Application

1-Oleoyl-rac-glycerol has been used:
  • to mix with the sample by two-syringe method, to achieve lipidic cubic phase in crystallization technique
  • as a substrate for monoglyceride (MG) lipase assay
  • in the preparation of MG solution for the measurement of in vitro MG hydrolase activity

Packaging

1 g in poly bottle
25, 50, 100 mg in poly bottle

Biochem/physiol Actions

1-Oleoyl-rac-glycerol shows both inhibition and anti-inhibition action on the lipoprotein lipase mediated triglyceride hydrolysis.
Monoolein (1-Oleoyl-rac-glycerol) is used in the development of monoolein-based nanoparticulate liquid dispersions as possible vehicles for drug delivery.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

309.2 °F - closed cup

Flash Point(C)

154.0 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Product Information Sheet

More Documents

Quotes and Ordering

Recent Advances in Environmentally Compatible Polymers: Cellucon?99 Proceedings, 205-205 (2001)
Thomas G Meikle et al.
Journal of colloid and interface science, 587, 90-100 (2020-12-29)
The growing global threat of antimicrobial resistance, combined with the slowed development of novel antibiotics, has resulted in a critical need for new antimicrobial therapies. Naturally occurring antimicrobial peptides (AMPs) can act as highly potent, broad-spectrum antibiotics which may be
Assays of lipolytic enzymes
Adipose Tissue Protocols, 97-119 (2001)
Measurement of lipolysis
Methods in Enzymology, 538, 171-193 (2014)
Elisabetta Esposito et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 80(2), 306-314 (2011-11-09)
The physico-chemical properties and in vivo efficacies of two nanoparticulate systems delivering the antiparkinsonian drug bromocriptine (BC) were compared in the present study. Monoolein Aqueous Dispersions (MADs) and Nanostructured Lipid Carriers (NLCs) were produced and characterized. Cryogenic transmission electron microscopy

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