M8902

Sigma-Aldrich

MES hemisodium salt

≥98% (titration)

Synonym(s):
4-Morpholineethanesulfonic acid hemisodium salt, 2-(N-Morpholino)ethanesulfonic acid hemisodium salt
Empirical Formula (Hill Notation):
C6H13NO4S·0.5Na
CAS Number:
Molecular Weight:
206.73
MDL number:
eCl@ss:
32129211
PubChem Substance ID:
NACRES:
NA.25
Pricing and availability is not currently available.

assay

≥98% (titration)

form

crystalline powder

impurities

≤8% water content (Karl Fischer)

useful pH range

5.5 - 6.7

pKa 

6.1

solubility

water: 500 mg/mL, clear, colorless

cation traces

Pb: ≤5 ppm

SMILES string

Na+.OS(=O)(=O)CCN1CCOCC1.O-S(=O)(=O)CCN2CCOCC2

InChI

1S/2C6H13NO4S.Na/c2*8-12(9,10)6-3-7-1-4-11-5-2-7;/h2*1-6H2,(H,8,9,10);/q;;+1/p-1

InChI key

KHQSUKMBWPKXOP-UHFFFAOYSA-M

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RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Vimala N Bharadwaj et al.
Tissue engineering. Part A, 26(13-14), 688-701 (2020-07-23)
The development of effective therapeutics for brain disorders is challenging, in particular, the blood-brain barrier (BBB) severely limits access of the therapeutics into the brain parenchyma. Traumatic brain injury (TBI) may lead to transient BBB permeability that affords a unique...
Vimala N Bharadwaj et al.
Nanomedicine : nanotechnology, biology, and medicine, 14(7), 2155-2166 (2018-06-23)
Clinically, traumatic brain injury (TBI) results in complex heterogeneous pathology that cannot be recapitulated in single pre-clinical animal model. Therefore, we focused on evaluating utility of nanoparticle (NP)-based therapeutics following three diffuse-TBI models: mildclosed-head injury (mCHI), repetitive-mCHI and midline-fluid percussion...
Magnus Rogeberg et al.
Biochimie, 105, 216-220 (2014-07-11)
Deposition of insoluble amyloid plaques is one of the known hallmarks of Alzheimer's disease. Amyloid beta 1-42 is the main component in these plaques, and the soluble oligomers of this peptide are believed to contribute to synaptic degradation and dementia....

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