M9035

IgG1, Kappa from murine myeloma

clone MOPC 31C, purified immunoglobulin, buffered aqueous solution

• Synonym(s): Mouse IgG1-κ
• MDL number: MFCD00164798
• NACRES: NA.46

Properties

• biological source: mouse
• Quality Level: 200
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• clone: MOPC 31C, monoclonal
• Assay: ≥95% (gel filtration, HPLC)
• form: buffered aqueous solution
• concentration: ≥1 mg/mL
• shipped in: dry ice
• storage temp.: −20°C

Description

General description

Immunoglobulins (Igs) belongs to the immunoglobulin super-family. IgG is the abundant immunoglobulin in human serum. The four classes of IgG can be IgG1, IgG2, IgG3 and IgG4.

Mammalian immunoglobins contain either lambda or kappa light chains.

Specificity

Specificity is determined by mouse monoclonal isotyping strips. The purified immunoglobulin preparation is non-reactive with mouse IgA, IgM, IgG2a, IgG2b, or IgG3.

Application

IgG1, Kappa from murine myeloma has been used in:

• chromatin immunoprecipitation (ChIP)
• immunofluorescence
• immunocapture
• enzyme immunoassay
• immunohistochemistry

Biochem/physiol Actions

IgG1 is the most abundant and its deficiency results in hypogammaglobulinemia. IgG antibody have enormous therapeutic potential and the Fc region is involved the development of therapeutic antibody.

Physical form

Solution in 0.02 M Tris buffered saline, pH 8.0, containing 0.02% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves