M9771

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M9771

N-Methoxysuccinyl-Ala-Ala-Pro-Val-7-amido-4-methylcoumarin

elastase substrate

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Synonym(s):

MeOSuc-AAPV-AMC

Empirical Formula (Hill Notation):

C₃₁H₄₁N₅O₉

CAS Number:

72252-90-5

Molecular Weight:

627.69

MDL number:

MFCD00077135

PubChem Substance ID:

24897367

NACRES:

NA.32

Quality Level

200

Assay

≥98% (HPLC)

form

powder

solubility

chloroform: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

COC(=O)CCC(=O)NC(C)C(=O)NC(C)C(=O)N1CCCC1C(=O)NC(C(C)C)C(=O)Nc2ccc3C(C)=CC(=O)Oc3c2

InChI

1S/C31H41N5O9/c1-16(2)27(30(42)34-20-9-10-21-17(3)14-26(39)45-23(21)15-20)35-29(41)22-8-7-13-36(22)31(43)19(5)33-28(40)18(4)32-24(37)11-12-25(38)44-6/h9-10,14-16,18-19,22,27H,7-8,11-13H2,1-6H3,(H,32,37)(H,33,40)(H,34,42)(H,35,41)

InChI key

CMEUDEVBFFPSEI-UHFFFAOYSA-N

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This Item	S9761	S8758	S0763
Sigma-Aldrich M9771 N-Methoxysuccinyl-Ala-Ala-Pro-Val-7-amido-4-methylcoumarin	Sigma-Aldrich S9761 N-Succinyl-Ala-Ala-Pro-Phe-7-amido-4-methylcoumarin	Sigma-Aldrich S8758 N-Succinyl-Ala-Ala-Phe-7-amido-4-methylcoumarin	Sigma-Aldrich S0763 N-Succinyl-Ala-Phe-Lys 7-amido-4-methylcoumarin acetate salt
assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥98%	assay ≥95% (TLC)
form powder	form powder	form powder	form powder
solubility chloroform: 50 mg/mL, clear, colorless	solubility methanol: 50 mg/mL, clear, colorless	solubility 50% acetic acid: 1 mg/mL, clear, colorless	solubility 1 M NH4OH: 50 mg/mL, clear to slightly hazy, colorless to light yellow
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 100

Application

N-Methoxysuccinyl-Ala-Ala-Pro-Val-7-amido-4-methylcoumarin has been used as a substrate in elastase assay using bone marrow lysates and pancreatic lysates.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Substrates

Fluorogenic substrate for the assay of human leukocyte and porcine pancreatic elastase.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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