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MAK059

Sigma-Aldrich

Formate Assay Kit

sufficient for 100 colorimetric tests

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UNSPSC Code:
12161503
NACRES:
NA.84

usage

sufficient for 100 colorimetric tests

application(s)

cosmetics
environmental
food and beverages

detection method

colorimetric

storage temp.

−20°C

General description

Formate, the salt form of formic acid, is the simplest carboxylate anion. Formate is produced in the mitochondria as a result of the oxidation of one-carbon donors such as serine. Mitochondrially-derived formate is utilized for cytoplasmic one-carbon metabolism in the de novo synthesis of purines, thymdiylate, and the remethylation of homocysteine to methionine. Under normal physiologic conditions, formate is present at low levels in serum and blood but levels may be increased following acute methanol poisoning or environmental exposure to formaldehyde. Serum and urine formate levels were increased in vitamin B12-deficient rats and may be indicative of hyperhomocysteinemia due to defects in remethylation.

Application

Formate Assay kit has been used to determine the concentration of formate in samples.

Suitability

Suitable for serum, urine, media, cells, and tissues.

Principle

The Formate Assay Kit provides a simple, sensitive, and rapid means of quantifying formate in a variety of samples including serum, urine, media, cells, and tissues. Formate concentrations are determined by an enzymatic assay, which results in a colorimetric (450 nm) product, proportional to the formate present.

Other Notes

For additional information on our range of Biochemicals, please complete this form.

pictograms

Health hazardCorrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B

wgk_germany

WGK 3


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Providing reducing power by microalgal photosynthesis: a novel perspective towards sustainable biocatalytic production of bulk chemicals exemplified for aliphatic amines
Lowe J, et al.
Scientific Reports, 8, 10436-10436 (2018)
Benjamin J Koestler et al.
mBio, 9(5) (2018-09-27)
The intracellular human pathogen Shigella flexneri invades the colon epithelium, replicates to high cell density within the host cell, and then spreads to adjacent epithelial cells. When S. flexneri gains access to the host cytosol, the bacteria metabolize host cytosolic
Henning Kirst et al.
Proceedings of the National Academy of Sciences of the United States of America, 119(8) (2022-02-24)
Formate has great potential to function as a feedstock for biorefineries because it can be sustainably produced by a variety of processes that don't compete with agricultural production. However, naturally formatotrophic organisms are unsuitable for large-scale cultivation, difficult to engineer
Ho Shing Chan et al.
Frontiers in microbiology, 12, 654033-654033 (2021-05-11)
Klebsiella pneumoniae with crude glycerol-utilizing and hydrogen (H2)-producing abilities was successfully isolated from return activated sludge from Shatin Sewage Treatment Works. The H2 production strategy used in this study was optimized with crude glycerol concentrations, and 1,020 μmol of H2
Oscar A Sosa et al.
Applied and environmental microbiology, 85(13) (2019-04-28)
The marine unicellular cyanobacterium Prochlorococcus is an abundant primary producer and widespread inhabitant of the photic layer in tropical and subtropical marine ecosystems, where the inorganic nutrients required for growth are limiting. In this study, we demonstrate that Prochlorococcus high-light

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