May-Grünwald Stain has been employed to stain neutrophil granules and granulocyte inclusion bodies. May-Grünwald-Giemsa might be useful in the diagnosis of Malassezia folliculitis, a fungal mediated disorder.
For use in the differential staining of cellular elements of blood
Prepared with non-polychromed (non-oxidized) methylene blue and eosin Y.
Proceedings of the National Academy of Sciences of the United States of America, 117(26), 14779-14789 (2020-06-21)
Hematological analysis, via a complete blood count (CBC) and microscopy, is critical for screening, diagnosing, and monitoring blood conditions and diseases but requires complex equipment, multiple chemical reagents, laborious system calibration and procedures, and highly trained personnel for operation. Here
Heme-iron recycling from senescent red blood cells (erythrophagocytosis) accounts for the majority of total body iron in humans. Studies in cultured cells have ascribed a role for HRG1/SLC48A1 in heme-iron transport but the in vivo function of this heme transporter
Gaucher iPSC-derived macrophages produce elevated levels of inflammatory mediators and serve as a new platform for therapeutic development.
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