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MSKT0001

Sigma-Aldrich

SILuMAb K1 Pharmacokinetic Kit

Synonym(s):
PK Kit
Pricing and availability is not currently available.

suitability

suitable for mass spectrometry

storage temp.

2-8°C

Related Categories

General description

All critical reagents necessary to perform the assay are provided in the kit. The plate-based format avoids the high cost and potential LC column blockage associated with bead-based enrichment formats. Sample preparation with the SILuMAb PK kit can be performed in under 5 hours and consists of coating wells with high-specificity capture antibody, followed by immunoaffinity enrichment and rapid, in-plate trypsin digestion. The resulting digest is ready for injection, with no SPE or other cleanup required.

Application

The SILuMAb K1 Pharmacokinetic (PK) kit enables a robust, high-throughput assay for quantification of human IgG1 antibody in animal sera by LC-MS/MS.

Storage and Stability

Store the kit at 2-8°C. The kit is stable for two years refrigerated.

Legal Information

SILu is a trademark of Sigma-Aldrich Co. LLC

Signal Word

Danger

RIDADR

UN 3316 9

Flash Point(F)

75.2 °F

Flash Point(C)

24 °C

Articles
In this study, we developed a rapid trypsin digest kit that, at elevated temperatures, yielded reliable, reproducible results in less than 2 hours on a wide variety of substrates for mass spectrometry.
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Protocols
Pharmacokinetic (PK) kit enables a robust, high-throughput assay for quantification of human IgG1 antibody in animal sera by LC-MS/MS.
Read More

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