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MSQC24

Sigma-Aldrich

SILuLite SigmaMAb Pembrolizumab Monoclonal Antibody

recombinant, expressed in CHO cells

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Synonym(s):
Biologic Antibody Mimic, Biotherapeutic Antibody Mimic, Monoclonal Antibody Calibrator

recombinant

expressed in CHO cells

Quality Level

assay

≥90% (HPLC)

form

solid

suitability

suitable for mass spectrometry

shipped in

wet ice

storage temp.

−20°C

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This Item
MSQC28MSQC25MSQC14
form

solid

form

solid

form

solid

form

solid

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

recombinant

expressed in CHO cells

recombinant

expressed in CHO cells

recombinant

expressed in CHO cells

recombinant

expressed in CHO cells

assay

≥90% (HPLC)

assay

≥90% (HPLC)

assay

≥90% (HPLC)

assay

≥90% (SDS-PAGE)

General description

SigmaMAb Pembrolizumab (MSQC24) was designed to be a standard for the analysis of Pembrolizumab monoclonal antibodies using mass spectrometry. An isotopically labeled version is available as SILuMab Pembrolizumab (MSQC25).

SigmaMAb Pembrolizumab is for research use only and is not intended for diagnostic or therapeutic use.

Sequence

SigmaMAb Pembrolizumab Heavy Chain:
QVQLVQSGVEVKKPGASVKVSCKASGYTFTNYYMYWVRQAPGQGLEWMGGINPSNGGTNFNEKFKNRVTLTTDSSTTTAYMELKSLQFDDTAVYYCARRDYRFDMGFDYWGQGTTVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYGPPCPPCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLG

SigmaMAb Pembrolizumab Light Chain:
EIVLTQSPATLSLSPGERATLSCRASKGVSTSGYSYLHWYQQKPGQAPRLLIYLASYLESGVPARFSGSGSGTDFTLTISSLEPEDFAVYYCQHSRDLPLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC

Legal Information

SILu is a trademark of Sigma-Aldrich Co. LLC

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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