Skip to Content
MilliporeSigma

MSQC8

Sigma-Aldrich

SigmaMAb Antibody Drug Conjugate (ADC) Mimic

Antibody Cysteine-Fluorophore Conjugate Standard

Synonym(s):

Antibody Drug Conjugate

Slide 1 of 1
Sign Into View Organizational & Contract Pricing

Select a Size

0.5 MG
$786.00

$786.00


Check Cart for Availability

Request a Bulk Order

Select a Size

Change View
0.5 MG
$786.00

About This Item

UNSPSC Code:
12352204
NACRES:
NA.32

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

$786.00


Check Cart for Availability

Request a Bulk Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

recombinant

expressed in CHO cells

Quality Level

antibody product type

primary antibodies

form

lyophilized powder

shipped in

wet ice

storage temp.

−20°C

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
MSQC28MSQC26MSQC4
storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

form

lyophilized powder

form

solid

form

solid

form

-

recombinant

expressed in CHO cells

recombinant

expressed in CHO cells

recombinant

expressed in CHO cells

recombinant

expressed in CHO cells

antibody product type

primary antibodies

antibody product type

-

antibody product type

-

antibody product type

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

General description

SigmaMab Antibody Drug Conjugate (ADC) Mimic, is a non-toxic drug mimic that is utilized as a standard for mass spectrometry and high performance liquid chromatography. The ADC Mimic conjugates SigmaMab (MSQC4), an IgG1 monoclonal antibody, to dansyl fluorophores via an LC-SMCC crosslinker. This dansyl-LC-SMCC attachment serves as the substitution for the toxic payload of a real ADC.

The ADC Mimic allows for safer and more consistent testing, making it the optimal product over real ADCs. It is also a more affordable product compared to real ADCs. With the help of this non-toxic product, LC-MS processes can be developed in a safer environment.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Questions

1–2 of 2 Questions  
  1. Is the primary sequence of the antibody available?

    1 answer
    1. SigmaMAb Antibody Drug Conjugate (ADC) Mimic consists of the human universal monoclonal antibody standard (Catalog Number MSQC4, an IgG1 monoclonal antibody) conjugated to dansyl fluorophores via an LC-SMCC crosslinker.

      The sequence of MSQC4 can be found in the user guide. Sequence Information:

      1. SigmaMAb Heavy Chain:
      EVQLVESGGGLVQPGGSLRLSCVASGFTLNNYD MHWVRQGIGKGLEWVSKIGTAGDRYYAGSVKGR FTISRENAKDSLYLQMNSLRVGDAAVYYCARGAG RWAPLGAFDIWGQGTMVTVSSASTKGPSVFPLA PSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGA LTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQ TYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCP APELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVD VSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNS TYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPI EKTISKAKGQPREPQVYTLPPSRDELTKNQVSLT CLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDS DGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALH NHYTQKSLSLSPG

      2. SigmaMAb Light Chain:
      QSALTQPRSVSGSPGQSVTISCTGTSSDIGGYNF VSWYQQHPGKAPKLMIYDATKRPSGVPDRFSGS KSGNTASLTISGLQAEDEADYYCCSYAGDYTPGV VFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANK ATLVCLISDFYPGAVTVAWKADSSPVKAGVETTT PSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVT HEGSTVEKTVAPTECS

      Helpful?

  2. Does MSQC8 (SigmaMAb Antibody Drug Conjugate (ADC) Mimic) has light chain lambda or gamma?

    1 answer
    1. This antibody has both lambda light chains and gamma heavy chains.

      Helpful?

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service