N0632

β-Nicotinamide adenine dinucleotide sodium salt

• Synonym(s): β-DPN, β-NAD, Coenzyme 1, Cozymase, DPN, Diphosphopyridine nucleotide, NAD, Nadide
• Empirical Formula (Hill Notation): C₂₁H₂₆N₇NaO₁₄P₂
• CAS Number: 20111-18-6
• Molecular Weight: 685.41
• MDL number: MFCD00148917
• UNSPSC Code: 41106305
• PubChem Substance ID: 24897433
• NACRES: NA.51

Properties

• assay: ≥95% (HPLC); ≥95% (enzymatic); ≥95% (spectrophotometric assay)
• Quality Level: 300
• form: powder
• solubility: H₂O: soluble-50 mg/mL, clear, colorless to faintly yellow
• storage temp.: −20°C
• SMILES string: [Na].NC(=O)C1=CC=C[N](=C1)C2OC(COP(O)(=O)OP(O)(=O)OCC3OC(C(O)C3O)n4cnc5c(N)ncnc45)C(O)C2O
• InChI: 1S/C21H28N7O14P2.Na.H/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33;;/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H2,23,33)(H,34,35)(H,36,37)(H2,22,24,25);;
• InChI key: GSZRXOXBGUIRAU-UHFFFAOYSA-N
• Gene Information: human ... ESR1(2099), ESR2(2100)

Description

Biochem/physiol Actions

β-Nicotinamide adenine dinucleotide (NAD⁺) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD⁺:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD⁺/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases).

Electron acceptor

Other Notes

This is the common form of NAD.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves