N0649

Sigma-Aldrich

Anti-Neuronal Specific Enolase antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):
Anti-NSE
MDL number:
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

rat, human, mouse

application(s)

immunohistochemistry: suitable

conjugate

unconjugated

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

Gene Information

human ... ENO2(2026)

General description

Neuronal specific enolase 2 (ENO2) is also known as γ-enolase. It is present in the cytoplasm of neuroendocrine cells.

Immunogen

brain NSE from human.

Biochem/physiol Actions

Neuronal specific enolase 2 (ENO2) has been studied as a biomarker in the progression of multiple sclerosis. It converts 2-phosphoglycerate into phosphoenolpyruvate.

Physical form

Prediluted in 20 mM HEPES, containing 135 mM NaCI, 1% BSA, and 0.09% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Marcus W Koch et al.
Journal of the neurological sciences, 350(1-2), 46-50 (2015-02-18)
Previous studies suggested that serum neuron specific enolase (NSE) may be a biomarker associated with progression in MS. We measured serum NSE levels in 385 patients with multiple sclerosis (MS) (264 with relapsing-remitting (RR) MS, 86 with secondary progressive (SP)...
Jianbo Li et al.
Diabetes care, 36(11), 3405-3410 (2013-07-13)
To explore the relationship between serum neuron-specific enolase (NSE) levels and diabetic neuropathy. Type 1 or 2 diabetic and healthy control subjects (n = 568) were randomly enrolled in a cross-sectional study. Diabetic neuropathy status was documented by the presence...
Yoshinori Kawai
Frontiers in neuroanatomy, 12, 63-63 (2018-08-09)
To integrate and broadcast neural information, local microcircuits and global macrocircuits interact within certain specific nuclei of the central nervous system. The structural and functional architecture of this interaction was determined for the caudal nucleus of the tractus solitarius (NTS)...

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