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N1887

Neohesperidin

≥90% (HPLC)

Synonym(s):

(S)-4′-Methoxy-3′,5,7-trihydroxyflavanone-7-[2-O-(α-L-rhamnopyranosyl)-β-D-glucopyranoside], Hesperetin 7-O-neohesperidoside, NSC 31048

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About This Item

Empirical Formula (Hill Notation):
C28H34O15
CAS Number:
13241-33-3
Molecular Weight:
610.56
Beilstein/REAXYS Number:
74945
EC Number:
236-216-9
MDL number:
MFCD16661259
UNSPSC Code:
12352201
PubChem Substance ID:
24897534
NACRES:
NA.25

Key Documents

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biological source

plant (orange)

Quality Level

200

assay

≥90% (HPLC)

form

powder

color

white to light brown

mp

245.3  °C ((473.5 °F ) at 1,011 hPa - OECD Test)

solubility

pyridine: 20 mg/mL, clear, faintly yellow to yellow

storage temp.

2-8°C

SMILES string

COc1ccc(cc1O)[C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)cc3O2

InChI

1S/C28H34O15/c1-10-21(33)23(35)25(37)27(39-10)43-26-24(36)22(34)19(9-29)42-28(26)40-12-6-14(31)20-15(32)8-17(41-18(20)7-12)11-3-4-16(38-2)13(30)5-11/h3-7,10,17,19,21-31,33-37H,8-9H2,1-2H3/t10-,17-,19+,21-,22+,23+,24-,25+,26+,27-,28+/m0/s1

InChI key

ARGKVCXINMKCAZ-UZRWAPQLSA-N

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1 of 4

This Item
PHL897411458042H5254
Neohesperidin ≥90% (HPLC)

Sigma-Aldrich

N1887

Neohesperidin

Neohesperidin phyproof® Reference Substance

PHL89741

Neohesperidin

Neohesperidin United States Pharmacopeia (USP) Reference Standard

USP

1458042

Neohesperidin

Hesperidin ≥80% (HPLC)

Sigma-Aldrich

H5254

Hesperidin

assay

≥90% (HPLC)

assay

≥95.0% (HPLC)

assay

-

assay

≥80% (HPLC)

biological source

plant (orange)

biological source

-

biological source

-

biological source

Citrus sinensis (L.) Osbeck

Quality Level

200

Quality Level

-

Quality Level

-

Quality Level

200

solubility

pyridine: 20 mg/mL, clear, faintly yellow to yellow

solubility

-

solubility

-

solubility

soluble, yellow to brown

form

powder

form

powder

form

-

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

General description

Neohesperidin is a flavonoid. [1]

Application

Neohesperidin has been used in a study to assess the composition of shiikuwasha peels of different cultivation lines. [1] It has also been used in a study to investigate the protective effects of an extract from Citrus bergamia against inflammatory injury. [2]

Biochem/physiol Actions

Flavanone glycoside with neuroprotective and antioxidant properties. Does not inhibit oral carcinogenesis in a rat model unlike other citrus flavanones, but does exert a protective effect against gastritis and gastric lesions.

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000406361
0000406361
0000400480
0000394958
0000314409

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Adriana C E Graziano et al.
Life sciences, 90(25-26), 968-974 (2012-05-29)
The present work evaluated the anti-inflammatory/antioxidant activity of a well characterized extract from Citrus bergamia Risso and Poiteau (CBE), containing neoeriocitrin, naringin, neohesperidin and other flavonoids, on human NCTC 2544 keratinocytes treated with interferon-gamma (IFN-γ) and histamine (H). High performance
Agata Zygler et al.
Analytical and bioanalytical chemistry, 400(7), 2159-2172 (2011-04-06)
An analytical procedure involving solid-phase extraction (SPE) and high-performance liquid chromatography-mass spectrometry has been developed for the determination of nine high-intensity sweeteners authorised in the EU; acesulfame-K (ACS-K), aspartame (ASP), alitame (ALI), cyclamate (CYC), dulcin (DUL), neohesperidin dihydrochalcone (NHDC), neotame
B Aydeniz Güneşer et al.
Journal of food science and technology, 56(2), 634-642 (2019-03-25)
This study aims to report the composition of bioactives and volatile aromatic compounds, and determine the descriptive sensory properties of cold-pressed orange seed oil. The effects of oven pre-roasting and microwave pre-roasting of the seeds before cold pressing were compared.
Yonathan Asikin et al.
Journal of agricultural and food chemistry, 60(32), 7973-7980 (2012-07-19)
Citrus peels are important sources of various pleasant aroma compounds and valuable bioactive substances. To investigate differences in the composition and content of Shiikuwasha (Citrus depressa Hayata) peels from different cultivation lines, the composition of volatile aroma components, flavanones, and
Feng-Quan Tan et al.
BMC plant biology, 15, 89-89 (2015-04-08)
Polyploidy has often been considered to confer plants a better adaptation to environmental stresses. Tetraploid citrus rootstocks are expected to have stronger stress tolerance than diploid. Plenty of doubled diploid citrus plants were exploited from diploid species for citrus rootstock
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