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N4143

Sigma-Aldrich

Neurokinin B

≥95% (HPLC)

Synonym(s):
β-Neurokinin, Neuromedin K
Empirical Formula (Hill Notation):
C55H79N13O14S2
CAS Number:
Molecular Weight:
1210.42
MDL number:
PubChem Substance ID:
NACRES:
NA.32

Quality Level

Assay

≥95% (HPLC)

form

powder

UniProt accession no.

storage temp.

−20°C

SMILES string

CSCCC(NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(Cc2ccccc2)NC(=O)C(CC(O)=O)NC(=O)C(Cc3cnc[nH]3)NC(=O)C(CCSC)NC(=O)C(N)CC(O)=O)C(C)C)C(N)=O

InChI

1S/C55H79N13O14S2/c1-30(2)21-38(50(77)62-36(47(57)74)17-19-83-5)61-43(69)28-59-55(82)46(31(3)4)68-54(81)40(23-33-15-11-8-12-16-33)65-51(78)39(22-32-13-9-7-10-14-32)64-53(80)42(26-45(72)73)67-52(79)41(24-34-27-58-29-60-34)66-49(76)37(18-20-84-6)63-48(75)35(56)25-44(70)71/h7-16,27,29-31,35-42,46H,17-26,28,56H2,1-6H3,(H2,57,74)(H,58,60)(H,59,82)(H,61,69)(H,62,77)(H,63,75)(H,64,80)(H,65,78)(H,66,76)(H,67,79)(H,68,81)(H,70,71)(H,72,73)

InChI key

NHXYSAFTNPANFK-UHFFFAOYSA-N

Gene Information

human ... TAC3(6866)

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This Item
N6383N3762SML1686
Neurokinin B ≥95% (HPLC)

Sigma-Aldrich

N4143

Neurokinin B

Neurotensin ≥90% (HPLC)

Sigma-Aldrich

N6383

Neurotensin

Neuromedin B ≥90% (HPLC)

Sigma-Aldrich

N3762

Neuromedin B

Neoseptin-3 ≥98% (HPLC)

Sigma-Aldrich

SML1686

Neoseptin-3

assay

≥95% (HPLC)

assay

≥90% (HPLC)

assay

≥90% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

UniProt accession no.

Q9UHF0

UniProt accession no.

P30990

UniProt accession no.

-

UniProt accession no.

-

Gene Information

human ... TAC3(6866)

Gene Information

human ... NTS(4922)

Gene Information

-

Gene Information

-

Amino Acid Sequence

Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2

Biochem/physiol Actions

Neurokinin B is a ten-residue peptide. It is an endogenous tachykinin agonist with preference for the NK-3 receptor. It is a potent bronchoconstrictor and may have a neuromodulatory role in the brain. Neurokinin B has a role in slow synaptic or non-synaptic communication.

Other Notes

Lyophilized from 0.1% TFA in H2O

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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