Very good quality for the price. Have been buying this product for years and have had no issues.
N4382
Nalidixic acid sodium salt
powder
Nalidixic acid sodium salt
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Synonym(s):
1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid sodium salt
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About This Item
Empirical Formula (Hill Notation):
C12H11N2NaO3
CAS Number:
Molecular Weight:
254.22
Beilstein/REAXYS Number:
3580062
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.77
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form
powder
Quality Level
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
mode of action
DNA synthesis | interferes
enzyme | inhibits
originator
Sanofi Aventis
SMILES string
[Na+].CCN1C=C(C([O-])=O)C(=O)c2ccc(C)nc12
InChI
1S/C12H12N2O3.Na/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14;/h4-6H,3H2,1-2H3,(H,16,17);/q;+1/p-1
InChI key
ROKRAUFZFDQWLE-UHFFFAOYSA-M
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1 of 4
This Item | N8878 | 97023 | C8645 |
|---|---|---|---|
| form powder | form powder | form - | form powder or crystals |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 200 |
| originator Sanofi Aventis | originator - | originator - | originator - |
| antibiotic activity spectrum Gram-negative bacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum - | antibiotic activity spectrum Gram-negative bacteria |
| mode of action DNA synthesis | interferes | mode of action DNA synthesis | interferes, enzyme | inhibits | mode of action - | mode of action DNA synthesis | interferes, enzyme | inhibits |
General description
Chemical structure: quinolone
Nalidixic acid is a quinolone and can block the activity of bacterial topoisomerase type II enzyme, thereby stopping bacterial replication.[1] It is a potential antibacterial agent against Gram-negative bacteria than Gram-positive bacteria.[2] Nalidixic acid has been studied in the management of urinary tract infections.[3]
Application
Biochem/physiol Actions
Nalidixic acid sodium salt is an inhibitor of bacterial DNA polymerase (DNA gyrase) and avian myeloblastoma virus reverse transcriptase. Inhibits nucleic acid and protein synthesis in Saccharomyces cerevisiae.
Features and Benefits
This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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