N5413

Anti-Nestin antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

• Synonym(s): Anti-FJ21841, Anti-NES, Anti-Nbla00170
• UNSPSC Code: 12352203
• NACRES: NA.41
• MDL number: MFCD03455626
• Conjugate: unconjugated
• Clone: polyclonal
• Application: FACS, IHC, WB
• Citations: 87

Properties

• biological source: rabbit
• Quality Level: 200
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen ~110 kDa (cleaved), antigen ~177 kDa, antigen ~270 kDa
• species reactivity: rat, mouse, human
• concentration: ~1 mg/mL
• technique(s): flow cytometry: 1:200-1:500, immunohistochemistry: 1:100-1:200, western blot: 1:500-1:1,000
• UniProt accession no.: P48681
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... NES(10763) ; mouse ... Nes(18008) ; rat ... Nes(25491)

Description

General description

Nestin (NES) is a class VI cytoplasmic protein. It is expressed in the intermediate filaments and has a molecular weight of 177kDa. The gene encoding it is localized on human chromosome 1q23.1 with four exons.

Immunogen

synthetic peptide corresponding to residues 254-270 of human Nestin. This sequence is 93% identical in rat.

Biochem/physiol Actions

Nestin (NES) functions as a regulator of proteins which are involved in cell growth. It also interacts with other proteins of the intermediate filament. NES has been studied as a marker of neural stem cells.

Physical form

solution in phosphate buffered saline, containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)