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N5536

Sigma-Aldrich

Nefazodone hydrochloride

≥98% (HPLC), solid, selective serotonin reuptake inhibitor

Synonym(s):

2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl- 2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one hydrochloride, BMY-13754, MJ-13754-1, Serzone

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10 MG
$173.00
50 MG
$628.00

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10 MG
$173.00
50 MG
$628.00

About This Item

Empirical Formula (Hill Notation):
C25H32ClN5O2 · HCl
CAS Number:
Molecular Weight:
506.47
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

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$173.00


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Product Name

Nefazodone hydrochloride, ≥98% (HPLC), solid

Quality Level

assay

≥98% (HPLC)

form

solid

storage condition

desiccated

color

white

solubility

DMSO: ≥10 mg/mL
H2O: insoluble

originator

Bristol-Myers Squibb

SMILES string

O=C1N(CCCN2CCN(C3=CC=CC(Cl)=C3)CC2)N=C(CC)N1CCOC4=CC=CC=C4.Cl

InChI

1S/C25H32ClN5O2.ClH/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22;/h3-6,8-11,20H,2,7,12-19H2,1H3;1H

InChI key

DYCKFEBIOUQECE-UHFFFAOYSA-N

Gene Information

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This Item
1457902T6154A6226
AM251 >98% (HPLC), solid

A6226

AM251

form

solid

form

-

form

powder

form

solid

assay

≥98% (HPLC)

assay

-

assay

≥99% (HPLC)

assay

>98% (HPLC)

Quality Level

100

Quality Level

-

Quality Level

200

Quality Level

100

solubility

DMSO: ≥10 mg/mL, H2O: insoluble

solubility

-

solubility

45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble 23.3 mg/mL, methanol: soluble 25 mg/mL, clear, colorless, 0.1 M HCl: soluble 7.4 mg/mL, DMSO: soluble, H2O: soluble, hazy, colorless

solubility

DMSO: >10 mg/mL, H2O: insoluble

storage condition

desiccated

storage condition

-

storage condition

-

storage condition

-

color

white

color

-

color

-

color

white

Biochem/physiol Actions

Novel antidepressant; mixed 5-HT2A serotonin receptor antagonist/serotonin uptake inhibitor.

Features and Benefits

This compound was developed by Bristol-Myers Squibb. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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