N7381

β-Nicotinamide adenine dinucleotide hydrate

Grade AA-1

• Synonym(s): β-DPN, β-NAD, Coenzyme 1, Cozymase, DPN, Diphosphopyridine nucleotide, NAD, Nadide
• Empirical Formula (Hill Notation): C₂₁H₂₇N₇O₁₄P₂ · xH₂O
• CAS Number: 53-84-9
• Molecular Weight: 663.43 (anhydrous basis)
• MDL number: MFCD00036253
• eCl@ss: 39200202
• PubChem Substance ID: 24897823
• NACRES: NA.55

Properties

• biological source: yeast
• type: Grade AA-1
• form: powder
• IVD: not for in vitro diagnostic use
• color: white to off-white
• storage temp.: −20°C
• SMILES string: NC1=NC=NC2=C1N=CN2.O[C@@H]3[C@@H](COP(O)(OP(OC[C@@H](O4)[C@@H](O)[C@@H](O)[C@H]4[N+]5=CC=CC(C(N)=O)=C5)([O-])=O)=O)OC[C@@H]3O
• InChI: 1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
• InChI key: BAWFJGJZGIEFAR-NNYOXOHSSA-N

Description

General description

β-Nicotinamide adenine dinucleotide (β-NAD) is a ubiquitous biomolecule containing an adenylic acid and a nicotinamide-5′-ribonucleotide group linked together by a pyrophosphate moiety. In NAD⁺ complexes, the enzyme-cofactor interactions are highly conserved.

Application

β-Nicotinamide adenine dinucleotide hydrate has been used as a supplement in chocolate agar plates for Haemophilus influenzae growth.

Biochem/physiol Actions

β-Nicotinamide adenine dinucleotide (β-NAD) is an electron carrier and a cofactor, significantly involved in enzyme-catalyzed oxido-reduction processes and many genetic processes. NAD cycles between the oxidized (NAD⁺) and reduced (NADH) forms to maintain a redox balance necessary for continued cell growth. NAD is also involved in microbial catabolism. β-NAD acts as a substrate for various enzymes in several cellular processes.

Electron acceptor

Packaging

Packaged by solid weight.

Preparation Note

Produced by fermentation.

Other Notes

This is the common form of NAD.

Safety Information

• Pictograms: GHS08
• Signal Word: Warning
• Hazard Statements: H371
• Precautionary Statements: P260 - P264 - P270 - P308 + P311 - P405 - P501
• Hazard Classifications: STOT SE 2
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable