N7389

Sigma-Aldrich

3-Nitro-L-tyrosine

crystalline

Linear Formula:
O2NC6H3-4-(OH)CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
226.19
Beilstein/REAXYS Number:
2813157
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.32

Quality Level

form

crystalline

mp

233-235 °C (dec.) (lit.)

SMILES string

N[C@@H](Cc1ccc(O)c(c1)[N+]([O-])=O)C(O)=O

InChI

1S/C9H10N2O5/c10-6(9(13)14)3-5-1-2-8(12)7(4-5)11(15)16/h1-2,4,6,12H,3,10H2,(H,13,14)/t6-/m0/s1

InChI key

FBTSQILOGYXGMD-LURJTMIESA-N

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Packaging

5, 10, 25 g in poly bottle

Application

Marker for peroxynitrite.

Biochem/physiol Actions

Oxidant and cytotoxic agent.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Eman Ahmed Alaa El-Din et al.
Environmental science and pollution research international, 26(21), 21556-21564 (2019-05-28)
The evaluation of the toxicological effects of titanium dioxide nanoparticles (TiO2NPs) is increasingly important due to their growing occupational and industrial use. Curcumin is a yellow curry spice with a long history of use in herbal medicine and has numerous...
Tzu-Hao Li et al.
Scientific reports, 6, 39405-39405 (2016-12-23)
Thalidomide can modulate the TNFα-NFκB and iNOS pathway, which involve in the pathogenesis of hepatopulmonary syndrome (HPS) and muscle wasting in cirrhosis. In bile duct ligated-cirrhotic rats, the increased circulating CD16+ (inflammatory) monocytes and its intracellular TNFα, NFκB, monocyte chemotactic...
Ana C Andreazza et al.
Journal of neurochemistry, 127(4), 552-561 (2013-05-23)
Previously, we found decreased mitochondrial complex I subunits levels and increased protein oxidation and nitration in postmortem prefrontal cortex (PFC) from patients with bipolar disorder (BD) and schizophrenia (SCZ). The objectives of this study were to replicate our findings in...
John Y Ng et al.
Open biology, 3(2), 120148-120148 (2013-02-08)
Protein 3-nitrotyrosine is a post-translational modification that commonly arises from the nitration of tyrosine residues. This modification has been detected under a wide range of pathological conditions and has been shown to alter protein function. Whether 3-nitrotyrosine is important in...
Maren Carstensen et al.
European journal of clinical investigation, 43(4), 350-357 (2013-02-13)
Secreted frizzled-related protein 5 (Sfrp5) has been described as novel adipokine in mice with insulin-sensitising and anti-inflammatory properties similar to adiponectin. The aim of this study was to compare serum concentrations and determinants of Sfrp5, its pro-inflammatory antagonist wingless-type MMTV...

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