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N7627

Sigma-Aldrich

L-Norvaline

arginase inhibitor

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Synonym(s):
(S)-(+)-2-Aminopentanoic acid, (S)-2-Aminovaleric acid
Linear Formula:
CH3CH2CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
117.15
Beilstein/REAXYS Number:
1721162
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

assay

≥99% (TLC)

form

powder

color

white

mp

>300 °C (lit.)

application(s)

detection

SMILES string

CCC[C@H](N)C(O)=O

InChI

1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1

InChI key

SNDPXSYFESPGGJ-BYPYZUCNSA-N

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1 of 4

This Item
N6877N7502N8513
vibrant-m

N7627

L-Norvaline

-
vibrant-m

N6877

L-Norleucine

-
vibrant-m

N7502

DL-Norvaline

-
vibrant-m

N8513

L-Norleucine

Essential+ Grade
form

powder

form

powder

form

powder

form

powder or crystals

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

>300 °C

mp

>300 °C (lit.)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

color

white

color

white

color

white

color

white

application(s)

detection

application(s)

detection

application(s)

-

application(s)

detection

Biochem/physiol Actions

L-Norvaline enhances NO production from activated macrophages.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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C I Chang et al.
The American journal of physiology, 274(1 Pt 2), H342-H348 (1998-02-12)
In macrophages and many other cell types, L-arginine is used as a substrate by both nitric oxide synthase (NOS) and arginase to produce nitric oxide (NO) and urea, respectively. Because the availability of L-arginine is a major determinant for NO
Ying-Chen Lin et al.
The New phytologist, 223(4), 1904-1917 (2019-05-16)
Choline kinase catalyzes the initial reaction step of choline metabolism that produces phosphocholine, a prerequisite for the biosynthesis of a primary phospholipid phosphatidylcholine. However, the primary choline kinase and its role in plant growth remained elusive in seed plants. Here
Seyed Abdollah Hosseini et al.
International journal of molecular sciences, 20(4) (2019-03-01)
The importance of magnesium (Mg) for plant growth is well-documented. Silicon (Si)-mediated alleviation of mineral deficiencies has been also reported in a number of plant species; however, there is no report on the relevance of Si nutrition in plants grown
Nelson Machado et al.
Journal of the science of food and agriculture, 97(13), 4295-4305 (2017-03-10)
Freezing represents a common conservation practice regarding vegetal foodstuffs. Since compositional features need to be monitored during storage, the development of rapid monitoring tools suitable for assessing nutritional characteristics arises as a pertinent issue. In this study, cowpea (Vigna unguiculata
Mark R Sullivan et al.
Cell metabolism, 29(6), 1410-1421 (2019-03-25)
Tumors exhibit altered metabolism compared to normal tissues. Many cancers upregulate expression of serine synthesis pathway enzymes, and some tumors exhibit copy-number gain of the gene encoding the first enzyme in the pathway, phosphoglycerate dehydrogenase (PHGDH). However, whether increased serine

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