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N8513

Sigma-Aldrich

L-Norleucine

suitable for amino acid analysis, BioReagent

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Synonym(s):
(S)-(+)-2-Aminohexanoic acid, (S)-2-Aminocaproic acid
Linear Formula:
CH3(CH2)3CH(NH2)CO2H
CAS Number:
Molecular Weight:
131.17
Beilstein:
1721750
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

product line

BioReagent

form

powder or crystals

color

white

mp

>300 °C (lit.)

suitability

suitable for amino acid analysis

application(s)

detection

SMILES string

CCCC[C@H](N)C(O)=O

InChI

1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1

InChI key

LRQKBLKVPFOOQJ-YFKPBYRVSA-N

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1 of 4

This Item
N68776181984959
L-Norleucine suitable for amino acid analysis, BioReagent

Sigma-Aldrich

N8513

L-Norleucine

Essential+ Grade
L-Norleucine ≥98% (TLC)

Sigma-Aldrich

N6877

L-Norleucine

-
L-Leucine BioUltra, ≥99.5% (NT)

Sigma-Aldrich

61819

L-Leucine

Premium Grade
L-Serine BioUltra, ≥99.5% (NT)

Sigma-Aldrich

84959

L-Serine

Premium Grade
form

powder or crystals

form

powder

form

powder or crystals

form

powder or crystals

color

white

color

white

color

white

color

white

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

222 °C (dec.) (lit.)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

suitability

suitable for amino acid analysis

suitability

-

suitability

-

suitability

-

Application

Highly purified internal standard for all amino acid analysis methods.

Other Notes

Non-essential amino acid.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Amar R Mohite et al.
The Journal of organic chemistry, 77(12), 5423-5428 (2012-05-24)
A short, concise synthesis of enantiopure, side chain-modified α-amino acids such as 4-oxo-L-norvaline, 6-oxo-L-homonorleucine, and 5-cis-alkyl prolines is described. Knoevenagel condensation of l-aminocarboxylate-derived β-ketoesters with aldehydes followed by reductive decarboxylation results in unnatural α-amino acids in good yield. A fluorescent
L M FitzGerald et al.
Australian veterinary journal, 89(3), 95-100 (2011-02-18)
Four dogs presented with clinical signs of severe hepatic disease after consuming a commercial camel meat diet. Laboratory investigation revealed evidence of severe liver disease, including markedly increased serum alanine aminotransferase (ALT) activity and total bilirubin concentration, and prolonged clotting
Haiyan Wei et al.
The journal of physical chemistry. B, 114(36), 11820-11826 (2010-08-24)
Following the studies of urea denaturation of β-hairpins using molecular dynamics, in this paper, molecular dynamics simulations of two peptides, a 35 residue three helix bundle villin headpiece protein HP-35 and its doubly norleucine-substituent mutant (Lys24Nle/Lys29Nle) HP-35 NleNle, were undertaken
Jan Pícha et al.
Journal of enzyme inhibition and medicinal chemistry, 26(2), 155-161 (2010-06-29)
Ligands containing bulky aliphatic P1 residues exhibit a high affinity towards cytosolic leucine aminopeptidase, a bizinc protease of biomedical significance. According to this specificity, a series of phosphonic and phosphinic compounds have been put forward as novel putative inhibitors of
Alborz Mahdavi et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(1), 433-438 (2013-12-19)
Pathogenic microbes have evolved complex secretion systems to deliver virulence factors into host cells. Identification of these factors is critical for understanding the infection process. We report a powerful and versatile approach to the selective labeling and identification of secreted

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