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N9161

Sigma-Aldrich

Notch-2/Fc Chimera from rat

recombinant, expressed in NSO cells, ≥90% (SDS-PAGE), lyophilized powder

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About This Item

MDL number:
UNSPSC Code:
12352202
NACRES:
NA.26

biological source

rat

Quality Level

recombinant

expressed in NSO cells

assay

≥90% (SDS-PAGE)

form

lyophilized powder

mol wt

105-115 kDa by SDS-PAGE (reducing)
calculated mol wt 76.5 kDa

impurities

endotoxin, tested

UniProt accession no.

application(s)

cell analysis

storage temp.

−20°C

Gene Information

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Analysis Note

The biological activity is measured by its ability to bind Jagged-1.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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G Weinmaster et al.
Development (Cambridge, England), 116(4), 931-941 (1992-12-01)
Notch is a cell surface receptor that mediates a wide variety of cellular interactions that specify cell fate during Drosophila development. Recently, homologs of Drosophila Notch have been isolated from Xenopus, human and rat, and the expression patterns of these
G Weinmaster
Current opinion in genetics & development, 10(4), 363-369 (2000-07-13)
The Notch signaling pathway functions in a wide variety of processes that regulate tissue patterning and morphogenesis in developing vertebrates and invertebrates. Research on the mechanism of ligand-induced Notch signal transduction has revealed a novel and essential element in the

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