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O2375

Sigma-Aldrich

L-Ornithine monohydrochloride

≥99%

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Synonym(s):
(S)-2,5-Diaminopentanoic acid monohydrochloride
Empirical Formula (Hill Notation):
C5H12N2O2 · HCl
CAS Number:
Molecular Weight:
168.62
Beilstein:
3625847
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.26

Quality Level

Assay

≥99%

form

powder

impurities

ammonia and citrulline, essentially free

color

white

application(s)

cell analysis

SMILES string

Cl.NCCC[C@H](N)C(O)=O

InChI

1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/t4-;/m0./s1

Inchi Key

GGTYBZJRPHEQDG-WCCKRBBISA-N

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This Item
O4386O650357197
L-Ornithine monohydrochloride BioXtra, ≥99%

Sigma-Aldrich

O4386

L-Ornithine monohydrochloride

Premium Grade
L-Ornithine monohydrochloride analytical standard

Supelco

57197

L-Ornithine monohydrochloride

-
form

powder

form

powder

form

powder

form

powder

impurities

ammonia and citrulline, essentially free

impurities

ammonia- and citrulline-free, essentially free, ≤0.005% Phosphorus (P), ≤0.1% Insoluble matter

impurities

ammonia and citrulline, essentially free

impurities

-

color

white

color

white

color

-

color

white

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

application(s)

cell analysis

application(s)

-

application(s)

-

application(s)

clinical
food and beverages

Application

L-Ornithine monohydrochloride has been used to study the blocking effect of L-ornithine on the transport system that carries L-arginine for the overproduction of nitric oxide during lipopolysaccharide induced endotoxemia in rat model. It has also been used in decarboxylation test of amino acids.

Biochem/physiol Actions

L-Ornithine is a product of arginase degradation and plays an important role in ammonia metabolism via the urea cycle. In mammals, ornithine serves as a precursor for polyamines and proline biosynthesis. Spermine synthesized from ornithine, is an abundant polyamine observed in tumors such as breast carcinomas. Administration of L-ornithine is known to improve subjective index of sleep quality. L-ornithine reduces the cortisol/DHEA-S (dehydroepiandrosterone) ratio, that is associated with stress. In mice, L-ornithine is found to affect the levels of plasma growth hormone, corticosterone and melatonin levels in mice.

Other Notes

Product of arginine degradation by arginase

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Customers Also Viewed

Arginase Activity in Human Breast Cancer Cell Lines: N?-Hydroxy-l-arginine Selectively Inhibits Cell Proliferation and Induces Apoptosis in MDA-MB-468 Cells
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THE EFFECT OF L-ORNITHINE ON THE INNER EAR OF RATS IN THE LIPOPOLYSACCHARIDE INDUCED ENDOTOXEMIA MODEL
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Kulak Burun bo?az Ihtisas Dergisi : KBB = Journal of Ear, Nose, and Throat (2018)
L-Ornithine affects peripheral clock gene expression in mice
Takafumi Fukuda
Scientific Reports (2016)
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